Stereochemistry of Knoevenagel Condensation Products from Cyanoacetates and Aromatic Aldehydes

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概要

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• The C-13 long-range selective proton decoupling method and x-ray crystallographic analysis were employed to determine the stereochemistry of the caffeic acid derivatives, extremely potent 12-lipoxygenase inhibitors, synthesized from cyanoacetates and aromatic aldehydes. The ester group of 1 and 2 was found to be trans to the phenyl group.

• 公益社団法人日本薬学会の論文
• 1991-12-25

著者

• 岩下 孝

  Suntory Institute for Bioorganic Research

• 長 秀連

  Suntory Institute for Biomedical Research

• 小山 嘉晃

  Suntory Institute for Biomedical Research

• 浜口 美樹子

  Suntory Institute for Biomedical Research

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