Central Cholinergic Agents. II. Synthesis and Acetylcholinesterase Inhibitory Activities of N-[ω-[N-Alkyl-N-(phenylmethyl)amino]alkyl]-3-arylpropenamides
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概要
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A series of N-[ω-[N-phenylmethyl)amino]alkyl-3-arylpropenamides was prepared and tested for its inhibitory activities on acetylcholinesterase. Some in the series were found to be potent inhibitors. The structure-activity relationships were discussed in detail.
- 公益社団法人日本薬学会の論文
- 1991-12-25
著者
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石原 雄二
Chemistry Research Laboratories
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後藤 義一
Chemistry Research Laboratories
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後藤 義一
Pharmaceutical Research Laboratories I Pharmaceutical Research Division Takeda Chemical Industries L
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加藤 浩紀
Biology Research Laboratories Research And Development Division Takeda Chemical Industries Ltd.
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石原 雄二
Pharmaceutical Research Laboratories I Pharmaceutical Research Division Takeda Chemical Industries L
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