Spectroscopic Investigation on the Mechanisms of Oxygenation Reactions of Skatole Catalyzed by Co (II) (p-OCH_3) TPP and ClCo (III) (p-OCH_3) TPP
スポンサーリンク
概要
- 論文の詳細を見る
Visible absorption spectra of 5,10,15,20-tetra (p-methoxyphenyl) porphyrinatocobalt (II) [Co (II) (p-OCH_3) TPP] and 5,10,15,20-tetra (p-methoxyphenyl) porphyrinatocobalt (III) chloride [ClCo (III) (p-OCH_3) TPP] were measured in toluene at room temperature in the absence or presence of O_2. Changes of the spectra due to the presence of skatole and/or pyridine were investigated. The spectra of four-coordinate cobalt complexes of 5,10,15,20-tetra (p-methoxyphenyl)-porphyrin were found to be practically indistinguishable from those of five-coordinate complexes, but clearly different from those of six-coordinate complexes, irrespective of the oxidation state of the central cobalt ion of complexes. The reaction medium for the oxygenation of skatole catalyzed by Co (II) (p-OCH_3) TPP showed only the spectrum of a six-coordinate complex, (skatole) Co (II) (p-OCH_3) TPP (O_2). This result showed clearly that the oxygenation of skatole must proceed through a ternary complex of the type (skatole)-[Co (II) complex]-(O_2). The addition of pyridine to the same reaction medium was found to produce a six-coordinate complex, (skatole) Co (II) (p-OCH_3) TPP (pyridine), irreversibly. This explains why the oxygenation of skatole is remarkably repressed upon addition of a Lewis base such as pyridine to the reaction medium. The spectrum of the reaction medium for the oxygenation of skatole catalyzed by ClCo (III) (p-OCH_3) TPP was found to consist of the superposed spectra of two six-coordinate complexes, ClCo (III) (p-OCH_3) TPP (O_2) and ClCo (III) (p-OCH_3) TPP (skatole). Therefore, the oxygenation of skatole apparently proceeds through the interaction between these two six-coordinate complexes.
- 社団法人日本薬学会の論文
- 1984-11-25
著者
-
上田 陽
Faculty of Pharmaceutical Sciences, Kyushu University
-
藤井 卓
Faculty Of Pharmaceutical Sciences Kyushu University Identification Section Oita Prefectural Police
-
小野 行雄
福山大学薬学部
-
上田 陽
九州大学薬学部
-
小野 行雄
Faculty of Pharmaceutical Sciences, Kyushu University
-
太田 睦子
Daiichi College of Pharmaceutical Sciences
-
香野 敬喜
Faculty of Pharmaceutical Sciences, Kyushu University
-
上田 陽
Faculty Of Pharmaceutical Sciences Kyushu University
関連論文
- Organic Analysis. XVI. Ultraviolet Spectral Study of Substituent Effect on Benzenesulfonamide
- 比旋光度計算と不斉合成による(+)-オキソプロパリンDの絶対配置決定に関する研究(発表論文抄録(2004))
- An Infrared Study of the C=N Stretching Frequency in N-Benzylideneaniline Derivatives
- ケイ素,リン,硫黄及び塩素を含む芳香族及び複素環化合物へのCNDO/S法の拡張(発表論文抄録(1985年))
- Extension of the CNDO/S Method to the Calculation of Aromatic and Heterocyclic Compounds Containing Si, P, S and Cl
- Spectroscopic Investigation on the Mechanisms of Oxygenation Reactions of Skatole Catalyzed by Co (II) (p-OCH_3) TPP and ClCo (III) (p-OCH_3) TPP
- π-π^* Transition Energies of Steroid Polyenes and Steroid Polyenyl Cations
- Studies on the Catalytic Oxidation Reactions of Skatole using Cobalt Complexes
- Quantum Chemical Study on the Cytochrome P-450-Catalyzed Hydroxylation of 1,2,3,4-Tetrahydronaphthalene and Indane
- Quantum Chemical Study on the Cytochrome P-450 catalyzed Hydroxylation of Aromatic Hydrocarbons
- Color Reaction Product of Urea with Diacetyl Monoxime and Glucuronolactone. III. Structures of Two Major Reaction Products of the Color Reaction of Butylurea with 1-Phenyl-1,2-propanedione
- Study on the Correspondence of Color Change with Polyenyl Cation Formation of Cholesterol in Strong Acids
- Tautomerism of 4-Amino- and 4-Arylamino-1,2-naphthoquinones
- 改良CNDO/Sによる有機化合物の電子スペクトル計算 : 一中心電子反発積分を改良した新しいCNDO/S計算(発表論文抄録(2006))
- アスパラギン酸405残基はアミノペプチダーゼBの基質特異性に寄与する(発表論文抄録(2006))
- 水溶液の差分空間分布関数による解析IV : エチレングリコールのgGg'からtGg'への配座変換過程における水和構造変化(発表論文抄録(2001))
- 水溶液の差分空間分布関数による解析III : 直鎖及び分岐型アルキル基を有するアルコールとエーテルの水和構造(発表論文抄録(2001))
- 水溶液の差分空間分布関数による解析II : ジメチルエーテル、180°エチルメチルエーテルおよび0°エチルメチルエーテルの水和構造(発表論文抄録(2001))
- モンテカルロ法による両親媒性分子の水和構造に関する研究
- メタノールおよびエタノール水溶液の差分空間分布関数による解析(発表論文抄録(2000))
- ペントアンスレン型構造を有する複素環化合物のモノアミン酸化酵素阻害活性(発表論文抄録(1991年))
- ペントアンスレン型構造を有する複素環化合物のモノアミン酸化酵素阻害活性
- Organic Analysis. XXV. Mechanism of the Reaction between Fructose and Diphenylamine
- Mechanism of the Reaction between Fructose and Diphenylamine
- Presumptive Structures of Activated Complexes in Polarographic Redox Reactions of Unsaturated Organic Compounds. II. Polarographic Oxidations of Aromatic Hydrocarbons, Aromatic Amines, Aromatic Bromides and Benzaldehyde Derivatives, and Polarographic Redu
- The Models for the Active Site of Pyridoxal Enzymes. Calculations of π-π^* Transition Energies of Electronic Absorption
- Substituent Effects on the Mass Spectra of ortho-Hydroxyaromatic Aldehyde para-Substituted Benzylidenehydrazones
- オルトーヒドロキシ芳香族アルデヒド, パラ置換ベンジリデンヒドラゾンの紫外吸収スペクトル
- 1,3,5-トリニトロベンゼンおよびピクリン酸から形成されるσ錯体のX線光電子スペクトル
- Molecular Orbital Interpretation of Infrared Absorption Frequencies. II. α, β-Unsaturated Carbonyl, para-and meta-Substituted Aromatic Carbonyl Compounds, an Introduction of the Mutual Additive Substituent Parameter
- Molecular Orbital Interpretation of Infrared Absorption Frequencies. I. Selection of HMO Hetero-atomic Parameters
- 大黄の煎液調製時におけるセンノシドA含量と瀉下活性(発表論文抄録(2003))
- 大黄の煎液調整時におけるセンノシドA含量と瀉下活性
- 漢方製剤中のバイカリン,オウゴノシド,バイカレイン,オウゴニン,ベルベリン,コプチシン,パルマチン,ヤテオリチン,グリチルリチンのイオンペア-HPLC法による同時定量分析(発表論文抄録(2000))
- Tricyanovinylation of Imidazole Derivatives with Tetracyanoethylene
- Mechanism of the Molisch Reaction
- Study on the Color Reaction Mechanism of the Seliwanoff Reaction with 4-Ethylresorcinol as the Color-Developing Reagent
- Interaction of Imidazole Derivatives with Electron Acceptors. II. Reaction Products of Imidazole with p-Benzoquinone
- オルトーヒドロキシ芳香族アルデヒド パラ置換ベンジリデンヒドラゾンのけい光スペクトルと核磁気共鳴スペクトルに見られる置換基効果
- 紫外部における多成分吸収帯の近似的ピーク解析法の研究
- Simulation of the Charge Relay Structure in Ribonuclease A
- 百瀬勉先生をしのぶ
- Color Reaction Mechanism of Cholesterol in Zak-Henly's Method. (Organic Analysis. LVII.)
- Color Reaction Mechanism of Cholesterol with Perchloric Acid, Phosphoric Acid and Ferric Chloride Reagent. I. (Organic Analysis. LVIII.)
- Color Reaction Product of Urea with Diacetyl Monoxime and Glucuronolactone. I. On the Reaction of Urea Derivatives with Diacetyl Monoxime and Glucuronolactone
- Molecular Orbital Interpretation of Infrared Absorption Frequencies. III. Nitrobenzene Derivatives, Cyano Compounds and an Application of Mutual Additive Substituent Parameters to Benzophenone Derivatives
- Studies on the Physical Properties of Aromatic Sulfinamides. II. Infrared Absorption Spectrum
- Organic Analysis. XIV. Infrared Spectra of Phenylsulfonyl Derivatives. (3). The C-H Deformation Vibrations of Benzene Ring, the CH_3 Rocking Frequencies of SO_2CH_3 Group, and the Characteristic Absorption Bands of SO_2NH_2 Group.
- Organic Analysis. XII. Infrared Spectra of Phenylsulfonyl Derivatives. (2). SO_2-Stretching Frequencies of Benzenesulfonamide Derivatives and CO-Stretching Frequencies of N-Acetylsulfonamide Groups.
- Organic Analysis. XVII. Some Observations on Ultraviolet Spectra of Phenyl Sulfone Derivatives
- 有機吸光光度法
- 質量スペクトルと分子構造の相互関係
- m-ジニトロベンゼン誘導体とシアン化アルカリの呈色反応機構(第3報) : 2,4-ジニトロフェノールとシアン化カリウムの反応生成物
- Interaction of Imidazole Derivatives with Electron-Acceptor. I. Isolation of Imidazolium 1,1,2,3,3-Pentacyanopropenide Derivatives
- Color Reaction Product of Urea with Diacetyl Monoxime and Glucuronolactone. II. On the Reaction of Butylurea with Diacetyl, 1-Phenyl-1,2-propanedione, 1-Phenyl-1-hydroxyimino-2-propanone, and 1-Phenyl-2-hydroxyimino-1-propanone
- Infrared Spectra of Phenylsulfonyl Derivatives. (4). The Infrared Spectra of N-Acylsulfonamide Derivatives. (Organic Analysis. XLVIII)
- Organic Analysis. LVI. Determination of Free Cholesterol in Blood Serum. An Application of Perchloric Acid-Phosphoric Acid-Ferric Chloride Reagent to Cholesteryl Digitonide.
- 芳香族スルフィンアミド誘導体の物理化学的性質の研究(第1報) : 核磁気共鳴スペクトルについて
- Organic Analysis. XXXVII. Reaction Mechanism of Mannuronic Acid and Galacturonic Acid with 1,3-Naphthalenediol.
- Organic Analysis. XXXIV. Reaction Mechanism of Glucuronic Acid with 1,3-Naphthalenediol.
- エレクトロンスペクトロスコピー
- Analysis of Daily Reports of Practical Training in Pharmacology using Text Mining