Reactions of Iminophosphoranes of α-Amino Acid Derivatives with Dimethyl Acetylenedicarboxylate. An Application to a Synthesis of 7α-Methoxycephalosporins
スポンサーリンク
概要
- 論文の詳細を見る
Thermolysis of phosphorus ylides (III and XIV), obtained by the reactions of the iminophosphoranes (II and XIII) with dimethyl acetylenedicarboxylate, afforded the imino derivatives (IV and XV) with elimination of triphenylphosphine. These imino compounds, IV and XV were methoxylated with lithium methoxide to yield the α-methoxy-amino-acid (X) and 7α-methoxy-cephalosporin (XVI), respectively.
- 公益社団法人日本薬学会の論文
- 1977-07-25
著者
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平岡 哲夫
New Lead Research Laboratories, Sankyo Co., Ltd.,
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平岡 哲夫
Central Research Laboratories, Sankyo Co., Ltd.
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平岡 哲夫
New Lead Research Laboratories Sankyo Co. Ltd.
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斉藤 外喜夫
Central Research Laboratories Sankyo Co. Ltd.
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