Synthesis of New Antimicrobials. V. Synthesis of Alkylenebis-(thiosemicarbazides) and Their Related Compounds
スポンサーリンク
概要
- 論文の詳細を見る
Several kinds of alkylenebis (thiosemicarbazide) and alkylenebis (bithiourea) derivatives were synthesized in order to examine their antimicrobial activity. 1,1'-Dibenzylidene-4,4'-alkylene-bis (thiosemicarbazides) were prepared from 4,4'-alkylene-bis (thiosemicarbazides) and arylaldehydes, and 1,1'-diaroyl-4,4'-hexamethylene-bis (thiosemicarbazides) were prepared by the reaction of 4', 4'-hexamethylene-bis (thiosemicarbazide) with aroyl chlorides. 1,1'-Dialkyl- or diaryl-6,6'-alkylene-bis (bithioureas) were synthesized from 4,4'-alkylene-bis (thiosemicarbazides) and alkyl or aryl isothiocyanates. N, N'-Hexamethylene-bis [2-amino-5-(2-methoxyphenyl) thiadiazole] was prepared by the ring closure of 1,1'-bis (2-methoxybenzylidene) -4,4'-hexamethylene-bis (thiosemicarbazide).
- 1975-03-25
著者
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木村 隆一
Reseach Institute For Production Development
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久木 正勝
Reseach Institute For Production Development
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藪内 隆弘
Reseach Institute For Production Development
関連論文
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