Reactions of Lactonic Compounds with Nitrogen-containing Reagents. II. Reaction of Meranzin with Dimethylamine or Piperidine
スポンサーリンク
概要
- 論文の詳細を見る
Synthetic meranzin (IVa) was treated with dimethylamine or piperidine in methanol at 40-42°(condition A) and in benzene at 150°(condition B). cis-Amides (VII) and (IX) and trans-amides (VIII) and (X) were obtained under conditions A and B, respectively. Re-examination of the reaction of natural IVa with dimethylamine under condition B revealed that the product was not V proposed by Bohme, et al. but one of the optical isomers of VIII. Treatment of natural IVa with dimethylamine under condition A gave one of the optical isomers of racemic VII. VII-VIII or IX-X equilibrium in ethanol induced by diffused light was also described.
- 公益社団法人日本薬学会の論文
- 1972-10-25
著者
-
村井 博
Research Laboratories Nippon Shinyaku Co. Ltd. Klinge Pharma Gmbh And Co.
-
村山 正雄
Research And Development Laboratory Nippon Shinyaku Co. Ltd.
-
尾崎 正邦
Research Laboratories, Nippon Shinyaku Co., Ltd.
-
仙福 健治
Research Laboratories, Nippon Shinyaku Co., Ltd. Klinge Pharma GmbH and Co.
-
角倉 達朗
Research and Development Laboratory, Nippon Shinyaku Co., Ltd.
-
尾崎 正邦
Research And Development Laboratory Nippon Shinyaku Co. Ltd.
-
仙福 健治
Research Laboratories Nippon Shinyaku Co. Ltd.
-
角倉 達朗
Research And Development Laboratory Nippon Shinyaku Co. Ltd.
関連論文
- Antitumor Activity of Acylated Oridonin
- New Hypocholesterolemic Abietamide Derivatives. I. Structure-activity Relationship
- Reactions of Lactonic Compounds with Nitrogen-containing Reagents. II. Reaction of Meranzin with Dimethylamine or Piperidine
- Reactions of Lactonic Compounds with Nitrogen-containing Reagents. I. Reaction of Byakangelicol with Dimethylamine and Piperidine
- New Hypocholesterolemic Abietamide Derivatives. II. Synthesis and Hypocholesterolemic Activity of N-Phenyl-Δ^8-dihydroabietamides
- Hypocholesterolemic Action of Tricyclic Diterpenoids in Rats
- Synthetic Studies on Suberosin and Osthol
- Synthesis of Homoesermethole.
- Synthesis of dl-Esermethole.
- Preparation of Some Phosphate Esters of 5-Methoxy-8-hydropsoralen
- Synthesis of 1-tert-Alkyl-6,7-dimethoxyisoquinolines.
- Synthesis of 1-Isoquinolylacetic Acid Derivatives.