Immunochemical Studies of Phospholipids. II. Syntheses of Cardiolipin and Its Analogues
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概要
- 論文の詳細を見る
Bis (dipalmitoyl D, L-α-glycerylphosphoryl)-1,3-glycerol disodium salt (I) was synthesized by the condensation of the silver salt of dipalmitoyl D, L-α-glycerophosphoric acid benzyl ester (XI) with 1,3-diiodopropanol benzyl ether, followed by debenzylation with sodium iodide and hydrogenolysis with palladium black. Bis (dipalmitoyl D, L-α-glycerylphosphoryl)-1,5-pentanediol disodium salt (III), bis (dipalmitoyl D, L-α-glycerylphosphoryl)-1,4-butanediol disodium salt (IV), bis (dipalmitoyl D, L-α-glycerylphosphoryl)-1,2-ethanediol disodium salt (VI) and bis (dipalmitoyl D, L-α-glycerylphosphoryl) methanediol disodium salt (VII) were synthesized similarly by the condensation of the silver salt (XI) with alkyl diiodide or dibromide, followed by debenzylation with sodium iodide. Bis (benzylphosphoryl)-1,3-propanediol disodium (X) was synthesized by condensation of silver dibenzyl phosphate with alkyl diiodide, followed by debenzylation with sodium iodide.
- 公益社団法人日本薬学会の論文
- 1968-01-25
著者
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井上 圭三
Faculty of Pharmaceutical Sciences, The University of Tokyo
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野島 庄七
帝京大・薬
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野島 庄七
Faculty Of Pharmaceutical Sciences University Of Tokyo
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- Immunochemical Studies of Phospholipids. II. Syntheses of Cardiolipin and Its Analogues
- On the Cardiolipin Analogues. Syntheses of Dipalmitoyl-D, L-α-glycerylphosphoryl-propanol Sodium Salt and Bis (dipalmitoyl-D, L-α-glyceryl-phosphoryl)-1,3-propanediol Disodium Salt.