The Antiscorbutic Activity of Some O-Benzoyl Derivatives of L-Ascorbic Acid in Guinea Pigs
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概要
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Some derivatives of L-ascorbic acid (L-AsA), including a monoester of the endiol group, were studied for their antiscorbutic activity in guinea pigs. Among them 2-O-benzoyl-L-AsA was found to have almost the same activity as that of L-AsA, i.e. even the oral dose equimolar to 1mg. of L-AsA/animal/day might be effective to prevent the development of scurvy. 2,6-Di-O-benzoyl-L-AsA and 3,5,6-tri-O-benzoyl-L-AsA were shown to be less active antiscorbutically, may be one-tenth or below, than L-AsA.
- 公益社団法人日本薬学会の論文
- 1966-09-25
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