Steroid Series. IX. A New Route to 6-Nitrosteroid Derivatives.
スポンサーリンク
概要
- 論文の詳細を見る
Treatment of cholesterol acetate (Ia), androst-5-ene-3β, 17β-diol diacetate (Ib), and 3β-hydroxyandrost-5-en-17-one acetate (Ic) with nitrosyl chloride afforded the corresponding 5α-chloro-6β-nitro compound in high yield. The adduct could be converted readily to a ⊿^5-6-nitro compound on treatment under basic conditions and also into a ⊿^4-3-oxo-6α-nitrosteroid derivative.
- 公益社団法人日本薬学会の論文
- 1962-12-25
著者
-
林 了三
三共(株)分析代謝研究所
-
林 了三
Takamine Laboratory, Sankyo CO., Ltd.
-
田辺 克巳
Takamine Laboratory, Sankyo Co., Ltd.
-
田辺 克巳
Central Research Laboratories Sankyo Co. Ltd.
-
田部 克巳
Central Research Laboratories Sankyo Co. Ltd.
関連論文
- 抗炎症薬にみる光学活性 : ロキソプロフェンの例(医薬品にみる光学活性)
- Purification and Some Properties of Ketone Reductase Forming an Active Metabolite of Sodium 2-[4-(2-Oxocyclopentylmethyl)-phenyl] propionate Dihydrate (Loxoprofen Sodium), a New Anti-inflammatory Agent, in Rabbit Liver Cytosol
- Structural Determination of Rat Urinary Metabolites of Sodium 2-[4-(2-Oxocyclopentylmethyl) phenyl] propionate Dihydrate (Loxoprofen Sodium), a New Anti-inflammatory Agent
- Optical Inversion of (2R)-to (2S)-Isomers of 2-[4-(2-Oxocyclopentylmethyl)-phenyl] propionic Acid (Loxoprofen), a New Anti-inflammatory Agent, and Its Monohydroxy Metabolites in the Rat
- Species Differences in Metabolism of Sodium 2-[4-(2-Oxocyclopentylmethyl)-phenyl]propionate Dihydrate (Loxoprofen Sodium), a New Anti-Inflammatory Agent
- Stereospecific Inversion of Configuration of 2-(2-Isopropylindan-5-yl)-propionic Acid in Rats
- Metabolic Studies on CS-359,a New β-Adrenergic Blocking Agent. I. Isolation and Identification of the Urinary Metabolites of CS-359
- Studies on the Total Synthesis of dl-Colchiceine. I. Synthesis of 3-Hydroxy-9,10,11-trimethoxy-1,2,3,4,6,7-hexahydro-5H-dibenzo [a, c] cycloheptatrien-5-one.
- Steroid Series. XVII. New Synthetic Routes to 19-Norsteroids (1)
- Steroid Series. XVI. The Preparation of 3α, 5α-Cyclo-6β, 19-oxidosteroids and its Conversion to 19-Oxygenated Steroid Derivatives
- Steroid Series. X. Ozonolysis of 7-Oxo-⊿^5-Steroids. An Attempt to synthesize 6-Azasteroid Hormone Analogs.
- The Formation of 6,19-Epoxy-3,5-cyclo-steroid
- Steroid Series. VI. : Synthesis of B-Norsteroids. (2).
- Steroid Series. V. : Synthesis of B-Norsteroids. (1).
- Steroid Series. IV. : Ozonization of Cyclic 3-(Ethylene Acetal) of ⊿^4-3-oxosteroids.
- Steroid Series. III. : Ozonization of 3-Acetoxy-⊿^5-steroids in the Presence of Formaldehyde.
- Steroid Series. II. Microbial Oxidation of Progesterone by Absidia regnieri
- Steroid Series. I. Microbial Oxidation of Steroids by Sclerotinia libertiana
- The Conversion of Alantolactone into Dihydroeudesmol
- Vitamin A及びその関連化合物の研究(第2報)Methylγ-Bromosenecioateによるβ-CyclocitralのReformatsky反応
- Steroid Series. XI. Synthesis of B-Norsteroid.
- Steroid Series. IX. A New Route to 6-Nitrosteroid Derivatives.
- The Structure of Alantolactone. III. Configurations of 4-Methyl Group in Tetrahydroalantolactone and Several 3-Hydroxytetrahydroalantolactones.
- The Structure of Alantolactone. II. The Conversion of Alantolactone into Dihydroeudesmol.
- Steroid Series. XXI. Reaction of 4-Halo-Δ^4-3-oxosteroides with Dimethyl Sulfoxide
- Steroid Series. XX. Reaction of α, β-Epoxyketone with Dimethyl Sulfoxide
- Steroid Series. XXIII. Photolysis of Steroidal 6-Oxygenated 5,19-Lactone (β-Lactone)
- 19-酸素化ステロイドの化学 : 19-ノルステロイドの合成
- Steroid Series. XXII. Photolysis of 3α, 5-Cyclo-6β-methoxy-17β-acetoxy-5α-androstan-19-one
- Steroid Series. XIX. Rearrangement Reactions of 3β-Acetoxy-6,19-dioxo-5α-steroids
- Steroid Series. XVIII. Acid-Catalysed Rearrangement Product of 3α, 5α-Cyclo-6,19-dioxosteroid and its Conversion to 19-Nor-A-homotestosterone