Revised Structure of Gonioheptolide A
スポンサーリンク
概要
- 論文の詳細を見る
(±)-Gonioheptolide A (3) was unambiguously synthesized from (±)-goniofupyrone (4) and thereby its structure was revised as (1'R^*, 2S^*, 3S^*, 4S^*, 5R^*)-3,4-dihydroxy-2-[(1'-hydroxy-2'-methoxycarbonyl)ethyl]-5-phenyl-tetrahydrofuran. Methanolysis of (±)-goniofupyrone (4) with conc.H_2SO_4 at room temperature provided (±)-gonioheptolide A (3) in 48% yield. The synthetic (±)-gonioheptolide A and its triacetate were comparable to natural gonioheptolide A and its triacetate, respectively.
- 公益社団法人日本薬学会の論文
- 1999-01-15
著者
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吉野 仁
阪大院薬
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HANAOKA Miyoji
Faculty of Pharmaceutical Sciences, Kanazawa University
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Mukai Chisato
Faculty Of Pharmaceutical Sciences Kanazawa University
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Hanaoka Miyoji
Faculty Of Pharmaceutical Sciences Kanazawa University
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Yamashita Haruhisa
Faculty Of Pharmaceutical Sciences Kanazawa University
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吉野 仁
Faculty Of Pharmaceutical Sciences Osaka University
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HIRAI Syuichi
Faculty of Pharmaceutical Sciences, Kanazawa University
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MCLAUGHLIN Jerry
Department of Medicinal Chemistry and Pharmacognosy School of Pharmacy and Pharmacal Sciences, Purdu
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Hirai S
Faculty Of Pharmaceutical Sciences Kanazawa University
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Mclaughlin Jerry
Department Of Medicinal Chemistry And Pharmacognosy School Of Pharmacy And Pharmacal Sciences Purdue
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