One-Pot Preparation of Chiral β-Amino Esters by Rhodium-Catalyzed Three-Components Coupling Reaction
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概要
- 論文の詳細を見る
Chiral β-amino esters are synthesized in one-pot from three components, amines, aldehydes, and ethyl bromoacetate, under the rhodium-catalyzed Reformatsky-type reaction condition, where complete diastereoselection is achieved in the nucleophilic addition step of ethyl bromoacetate to the imines prepared in situ.
- 公益社団法人日本薬学会の論文
- 2002-02-01
著者
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Honda T
Medicinal Chemistry Research Laboratories Sankyo Co. Ltd.
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HONDA Toshio
Faculty of Pharmaceutical Sciences, Hoshi University
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WAKABAYASHI Hitoshi
Faculty of Pharmaceutical Sciences, Hoshi University
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KANAI Kazuo
Faculty of Pharmaceutical Sciences, Hoshi University
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Honda Toshio
Faculty Of Pharmaceutical Sciences Hoshi University
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Kanai K
Faculty Of Pharmaceutical Sciences Hoshi University
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Wakabayashi H
Faculty Of Pharmaceutical Sciences Hoshi University
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Wakabayashi Hitoshi
Faculty Of Design Kyushu University
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