Studies on Tellurium-Containing Heterocycles. Part 22. Tellurazepine Ring System : Preparation of 1,5-Benzotellurazepin-4-ones and Their Conversion into Fully Unsaturated 1,5-Benzotellurazepines
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概要
- 論文の詳細を見る
The treatment of o-iodopropiolanilides (12), which were easily prepared from o-iodophenylisocyanate (11) and ethynylmagnesium bromide, with sodium hydrogen telluride resulted in the intramolecular ring closure of the presumed phenyltellurol intermediates (13) to a triple bond to give the l, 5-benzotellurazepin-4-ones (14) as the sole characterized products. The obtained amides (14) were easily converted into fully unsaturated lactim 4-methoxy-1, 5-benzotellurazepines (18) by treatment with trimethyloxonium tetrafluoroborate. Decomposition by thermolysis of the 4-methoxyazepinenes (18) afforded the 4-methoxyquinolines (19) with extrusion of a tellurium atom.
- 公益社団法人日本薬学会の論文
- 2004-04-01
著者
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Sashida Haruki
Faculty Of Pharmaceutical Sciences Hokuriku University
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Satoh H
Faculty Of Pharmaceutical Sciences Hokuriku University
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SATOH Hirohito
Faculty of Pharmaceutical Sciences, Hokuriku University
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