A Novel and Concise Synthesis of Spirodienone Alkaloids Using Hypervalent lodine(III) Reagents

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概要

• 論文の詳細を見る

• Intramolecular oxidative coupling reaction of N-protected benzyltetrahydroisoquinoline derivatives using hypervalent iodine(III) reagents was investigated. The use of remarkable combination of phenyliodine bis (trifluoroacetate) (PIFA) and heteropoly acid (HPA) in wet acetonitrile smoothly afforded morphinandienone alkaloids, while neospirinedienone alkaloids were obtained in high yield under anhydrous conditions.

• 社団法人日本薬学会の論文
• 2004-10-01

著者

• KITA Yasuyuki

  Graduate School of Pharmaceutical Sciences, Osaka University

• TOHMA Hirofumi

  Graduate School of Pharmaceutical Sciences, Osaka University

• Kita Yasuyuki

  Graduate School Of Pharmaceutical Sciences Osaka Univ.

• Kita Yasuyuki

  Graduate School Of Pharmaceutical Sciences Osaka University

• Tohma H

  Graduate School Of Pharmaceutical Sciences Osaka University

• Tohma Hirofumi

  Graduate School Of Pharmaceutical Sciences Osaka University

• HAMAMOTO Hiromi

  Graduate School of Pharmaceutical Sciences, Osaka University

• SHIOZAKI Yukiko

  Graduate School of Pharmaceutical Sciences, Osaka University

• HATA Kayoko

  Graduate School of Pharmaceutical Sciences, Osaka University

• Hata K

  Graduate School Of Pharmaceutical Sciences Osaka University

• Hamamoto Hiromi

  Graduate School Of Pharmaceutical Sciences Osaka University

• Shiozaki Yukiko

  Graduate School Of Pharmaceutical Sciences Osaka University

• Hata Kayoko

  Graduate School Of Pharmaceutical Sciences Osaka University

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• Novel Catalytic Asymmetric Sulfoxidation in Water Using the Hypervalent Iodine Reagent Iodoxybenzene
• A Novel and Concise Synthesis of Spirodienone Alkaloids Using Hypervalent lodine(III) Reagents
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