Synthesis, Analgesic, Anti-inflammatory and Antibacterial Activities of Some Novel 2-Phenyl-3-substituted Quinazolin-4(3H) Ones

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概要

• 論文の詳細を見る

• A series of novel 2-phenyl-3-substituted quinazolin-4(3H)-ones have been synthesized by treating methyl-N-(2-phenyl quinazolin-3-yl-4(3H)-one) dithiocarbamate with different amines, the starting material dithiocarbamate was synthesized from anthranilic acid. The title compounds were investigated for analgesic, anti-inflammatory and antibacterial activities. All the test compounds exhibited significant activity, the compounds A1, A2 and A3 shown more potent analgesic activity, and the compound A3 shown more potent anti-inflammatory activity than the reference standard diclofenac sodium.

• 公益社団法人日本薬学会の論文
• 2002-11-01

著者

• Salomon Viswas

  Medicinal Chemistry Laboratory S.b. College Of Pharmacy

• ALAGARSAMY Veerachamy

  Medicinal Chemistry Laboratory, Periyar College of Pharmaceutical Sciences for Girls

• Revathi R

  S.b.coll. Pharmacy Sivakasi Ind

• Revathi Rajappan

  Medicinal Chemistry Laboratory S.b.college Of Pharmacy

• VANIKAVITHA Gnanavel

  Medicinal Chemistry Laboratory, S.B. College of Pharmacy

• PALUCHAMY Veeran

  Medicinal Chemistry Laboratory, S.B. College of Pharmacy

• CHANDRAN Muniyandi

  Medicinal Chemistry Laboratory, S.B. College of Pharmacy

• Sujin Augustin

  Medicinal Chemistry Laboratory, S.B. College of Pharmacy

• THANGATHIRUPPATHY Arunachalam

  Medicinal Chemistry Laboratory, S.B. College of Pharmacy

• AMUTHALAKSHMI Sivaperuman

  Medicinal Chemistry Laboratory, S.B. College of Pharmacy

• Sujin Augustin

  Medicinal Chemistry Laboratory S.b. College Of Pharmacy

• Chandran Muniyandi

  Medicinal Chemistry Laboratory S.b. College Of Pharmacy

• Paluchamy Veeran

  Medicinal Chemistry Laboratory S.b. College Of Pharmacy

• Vanikavitha Gnanavel

  Medicinal Chemistry Laboratory S.b. College Of Pharmacy

• Alagarsamy V

  J.s.s. Coll. Pharmacy Mysore Ind

• Alagarsamy Veerachamy

  Medicinal Chemistry Laboratory J.s.s. College Of Pharmacy

• Amuthalakshmi Sivaperuman

  Medicinal Chemistry Laboratory S.b. College Of Pharmacy

• Thangathiruppathy Arunachalam

  Medicinal Chemistry Laboratory S.b. College Of Pharmacy

関連論文

• Synthesis and H_1-Antihistaminic Activity of Some Novel 1-Substituted-4-(3-methylphenyl)-1,2,4-triazolo[4,3-a]quinazolin-5(4H)-ones(Medicinal Chemistry)
• Synthesis, Analgesic, Anti-inflammatory and Antibacterial Activities of Some Novel 2-Phenyl-3-substituted Quinazolin-4(3H) Ones
• Synthesis, Analgesic and Anti-inflammatory Activities of Some Novel 2,3-Disubstituted Quinazolin-4(3H)-ones
• Synthesis and Pharmacological Evaluation of Some 3-(4-Methoxyphenyl)-2-substitutedamino-quinazolin-4(3H)-ones as Analgesic and Anti-inflammatory Agents
• Synthesis, Analgesic, Anti-inflammatory and Antibacterial Activities of Some Novel 2-Butyl-3-substituted Quinazolin-4-(3H)-ones(Medicinal Chemistry)
• Synthesis, Analgesic, Anti-inflammatory and Antibacterial Activities of some Novel 2-Methylthio-3-Substituted Quinazolin-4-(3H)-ones (Medicinal Chemistry)
• Synthesis, Analgesic, Anti-inflammatory and Antibacterial Activities of Some Novel 2-Methyl-3-substituted Quinazolin-4-(3H)-ones (Medicinal Chemistry)

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