PET測定におけるC^<15>O_2, ^<15>O_2定常吸入時の体内RI分布と臓器RI量の検討

概要

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Radioactivity absorption received by humans during C^<15>O_2 and ^<15>O_2 steady-state inhalation using a PET scanner were measured. Relative concentration of radioisotope absorption was measured using the profile scanning mode of the scanner. The volume(ml)of each organ was measured using computed tomography(CT). The accumulation of radioactivity(MBq・sec)in each organ was estimated from the radioactivity concentration(MBq・sec/ml)and volume(ml)of each organ. The radioactivity concentration was obtained using a brain and body emission scanning mode. In the profile image, high uptake organs, namely, the heart, brain, liver, kidneys were observed for C^<15>O_2 inhalation and for ^<15>O_2 inhalation, the heart and lungs were studied. The accumulated radioactivity in each organ was 12.3 MBq・sec for the brain, 13.7 MBq・sec for the lungs, 2.4 MBq・sec for the heart, 1.8 MBq・sec for the liver for C^<15>O_2(185 Mbq/min)inhalation, and for ^<15>O_2(555 MBq/min)inhalation, 11.8 MBq・sec for the brain, 84.8 MBq・sec for the lungs, 5.6 MBq・sec for the heart, 17.1 MBq・sec for the liver.
社団法人日本放射線技術学会の論文
1995-05-01