幼若イモリの排出腔周辺諸気管および生殖輸管の発達に及ぼす性ホルモン投与の効果

概要

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Testosterone or estradiol, or both were administered to young newts of Cynops pyrrhogaster, about one month after metamorphosis, for 28 days. The amount of the hormones injected intraperitoneally to each animal every 4 days was as follows: testosterone groups, 10 and 50μg; estradiol groups, 0.5 and 2.5μg; combination group, testosterone 10μg+estradiol 0.5μg. At the beginning of the experiment, no sexual difference was detected in any of the reproductive organs, exclusive of the gonads. Regardless of genetic sexes, the development of the male paracloacal organs and the Wolffian duct was remarkably stimulated in the testosterone groups. The application of estradiol alone had a slight stimulatory effect on the development of the spermatheca. The Wolffian duct was notably thick in the estradiol groups, although the epithelial cells of the duct were rather atrophic. A hypertrophy of the Mullerian duct was observed in the estradiol groups, and this change was more marked in the testosterone groups. In the combined testosterone and estradiol group, the effects of the hormones on the target organs were more or less antagonistic. No influence on the gonads was observed in any of the hormone-treated groups.
1979-06-25