魚類黒色素胞のアドレナリン凝集機構 : I.カテコールアミンの作用

スポンサーリンク

概要

• 論文の詳細を見る

• The responses of melanophores in the isolated scales of Oryzias latipes to four catecholamines, i.e. noradrenaline (NA), adrenaline (A), isoproterenol (ISO) and dopamine (D), and dichloro-isoproterenol(DCI) were quantitatively examined. All of the compounds except DCI induced concentration of pigments within both innervated and chronically denervated melanophores. Furthermore, the denervated melanophores were found to be supersensitive towards these amines. These results indicate that the catecholamines tested may act directly on the melanophores. The order of relative potency of the above catecholamines for causing pigment concentration and sensitivity change was NA and A> D> ISO on both innervated and denervated melanophores. DCI showed a weak concentrating effect only on innervated melanophores, indicating that it may also act indirectly on the cells. This drug inhibited the concentrating response of the melanophores by K ion, A and ISO. The following conclusions were reached regarding the relationship of chemical structures of these catecholamines to the direct action on melanophores. 1) N-isopropylation in the terminal amino group reduced the direct action. 2) The OH group on the beta carbon atom of the side chain may be important for contributing to the direct action, although it may not necessarily be essential for the action. 3) The phenolic OH groups on the phenyl ring may be essential for the direct action.

• 社団法人日本動物学会の論文
• 1968-01-15

著者

• 伊賀 哲郎

  島根大学文理学部生物学教室

関連論文

• ハマダンゴムシの円周運動(生理・生態)
• 両生類黒色素胞の顆粒運動と酸素(生理学)
• 非電解質溶液中での魚類黒色素胞の顆粒の凝集・拡散反応(細胞)
• 神経の退化, 再生過程でのメダカ黒色素胞のアドレナリン, シンパトール, チラミンに対する感受性変化
• メダカ摘出うろこ黄色素胞に対するKイオンの作用(生理・生化学)
• 魚類黒色素胞のアドレナリン凝集機構 : IV ノルメタネフリンおよびその関連物質の作用
• 魚類黒色素胞のアドレナリン凝集機構 : I.カテコールアミンの作用
• コイの孵化腺果粒の染色性
• 数種の魚類の孵化腺細胞の分布

スポンサーリンク