分離大豆タンパク質栄養による妊娠末期のラットへの影響

概要

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In our previous experiments decrease of food intake and fetal death during the last few days of pregnancy were observed in rats fed a diet of 10% soy protein isolate (SPI) throughout pregnancy. Fetal growth and maternal metabolism were studied on 19th and 20th day of pregnancy. Rats were fed on a 20% SPI diet and a 20% SPI+0.6% Met diet and a 10% purified whole egg protein (PEP) diet for control. The food intake and body weight of the 20% SPI diet groups decreased after 18th day of pregnancy. The concentrations of free amino acid and urea nitrogen in serum and amniotic fluid of the SPI diet groups showed higher values than those of the PEP diet group. Free fatty acid concentration in serum of the SPI diet groups was lower, while glucose concentration in serum of the SPI diet groups was higher than those values in serum of the PEP diet group, respectively. Estrogen values in urine of the SPI diet groups were higher than that of the PEP diet group in 19th day of pregnancy. These results suggested that during the last few days of pregnancy even a 20% SPI diet with a supplement of L-methionine was not sufficient for nutritional requirement of maternal rats and that SPI diets induced changes of endocrine system in pregnant rats.
社団法人日本家政学会の論文
1992-06-15