慢性関節リウマチに対するCryofiltrationの位置づけ

概要

論文の詳細を見る
Initially, we compared cryofiltration (CF) with leukapheresis (LA) regarding the effectiveness of each treatment on drug-resistant rheumatoid arthritis (RA) patients. Whereas CF seemed more effective than LA in controlling the disease activity of drug-resistant RA, the effect did not continue over 3 months after the cessation of CF. These data suggested the importance of adjuvant therapy following CF. Then, the advantage of adding CF together with D-penicillamine was demonstrated in controlling the disease activity of MTX-reslstant RA. Moreover, this phenomenon could be maintained for as long as 6 months after the discontinuation of CF. Our data strongly suggest that the simultaneous use of CF and DMARDs might enhance the effectiveness each drug in drug-resistant RA patients.
日本アフェレシス学会の論文
1998-10-31