続発性陰茎癌による持続勃起症の3例 : 附:本邦文献例について

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Case 1 , a 63 year old government official was admitted to our hospital on November 4, 1965, for asymptomatic hematuria. X-ray finding of his chest and other examinations were normal. Cystoscopy revealed almost major part of the cavity was occupied with a large bleeding tumor. Cystogram and arteriogram showed a gross tumor in the left wall. No function of the left kindey was found on IVP, renogram and renoscintigram. On November 15, 1965, partial resection of the bladder and left nephrectomy were performed. Histologically, the tumor was a transitional cell carcinoma with marked proliferation. Neither infiltration beyond the bladder wall nor metastasis to the left kidney and ureter was found. Anti-cancer therapy with Endoxan (cyclophosphamide, total 1100 mg) and irradiation by tele-cobalt (total fields doses 10989 r.) were carried out in the postoperative course. The patient was discharged on February 13, 1966. On April 27, 1966, no visible tumor in the bladder was found cystoscopically. From this time, penile erection without sexual libido was developed sometimes and then gradually its erection became almost constant. In June, the priapism became painful and tender. From July, the patient complained of disturbance of micturition and perineal pain when sitting for a long time. The patient was readmitted on July 28, 1966, on account of painful priapism. The glans and urethra were soft. The cavernous body was firm and mostly smooth except for the left side of the radix. Histological examination of a specimen obtained from radix of the penis revealed the transitional cell carcinoma. On August 12, 1966, total emasculation was performed. Cystoscopy after opertation showed no relapse of the bladder. The sections of the penile specimen were white-yellow, homogenous and firm, without hemorrhage and no property of cavernous body remained. The infiltration reached the submucosal tissue. In the subcutaneous tissue of the penis, several masses of the cancer tissue were seen in the blood vessels. Following the operation, anti-cancer therapy with Mitomycin C (total 50 mg) and tele-cobalt irradiation (5000 r.) were done.
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続発性陰茎癌による持続勃起症の3例 : 附:本邦文献例について

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