尿路感染症に対する腸溶性Panfuran Sの治験

概要

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Enteric-release Panfuran S was administered in 31 adult patients with urinary tract infections, containing 13 patients with acute cystitis, 18 chronic cystitis, 3 pyelitis. The patients were divided into 2 groups. No. 1) Administration was made in doses of 1g per day, 250mg 4 times a day, in 21 patients. No. 2) Administration was made in doses of 2g per day, 500mg 4 times a day, in 10 patients. Germs, sensitive-disc tests, urinary findings, subjective findings and side effects were discussed. Panfuran S was found to be the most sensitive drugs by the sensitive-disc tests, especially in the cases with mixed infection. No. 2 group showed more rapid improvement than No. 1 group by urinary findings. Especially patients with mixed infection were resistant to therapy. A remarkable improvement was obtained in 81% of No. 1 group and 90% of No. 2 group. Side effects were observed in 9.5% of No. 1 group and 40% of No. 2 group as digestive symptoms.
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