フレーム光度法による食品中のリチウムの定量

概要

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Lithium has been used as a medicine for the remedy and prevention of manic-depressive psychosis. It is, however, essential to monitor the blood lithium concentration of patients during their hospital-treatments, because the intake amount of lithium as a remedy is reflected in the blood lithium concentration, which is significantly close to a toxic level. Since continual lithium intake with daily meals is expected to prevent manic-depressive psychosis at an early stage, it is important to know the food lithium content. In this work, the effects of matrix constituents (Na^+, K^+, Ca^<2+>+, Mg^<2+> and PO_4^<3->) of food on the determination of lithium by flame photometry were studied. Since there was no interference of the matrix ions, the method was applied to food samples: fresh fish (30〜84 ng/g), dry-processed fish (731 and 1790 ng/g), table-salts (667〜2340 ng/g), infant formulas (120〜160 ng/g) and eastern medicines, such as mammalian bone and oyster-shell (18700 and 20200 ng/g).
社団法人日本分析化学会の論文
2004-01-05