カルシウム塩投与のビタミンB_2代謝に及ぼす影響 : (III) Ca/P比率ならびにカルシフェロール投与の尿中ビタミンB_2排泄量に及ぼす影響

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In previous papers, the author reported that urinary riboflavin excretion increased by the administraion of Ca-salts to rabbits. This time, in order to ascertain the effects of Ca/P ratio in the diet and the calciferol administration on the riboflavin metabolism, an experiment was carried out using 9 rabbits divided into 4 groups : 1st, Ca-gluconate injection ; 2nd, CaCO_3 and vitamin D_2 administration ; 3rd, Ca-gluconate injection with vitamin D_2 ; and the last, CaCO_3,KH_2PO_4 and vitamin D_2(Ca/P=0.6) administration, and the following results were obtained : not only CaCO_3+KH_2PO_4 group, but also that of Ca-salts alone showed comperative decrease of the urinary excretion of riboflavin by the administration of calciferol. In this way, the cause of the increase of urinary excretion of riboflavin by the administration of Ca-salts was ascertained to be the vitamin D deficiency in the diet.
日本ビタミン学会の論文