抗生物質共存下におけるビタミン類の微生物定量法 : (II)エリスロマイシン耐性の乳酸菌によるパントテン酸および葉酸の定量

概要

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The growth of Lactobacilli, usually used organisms for microbioassay, was completely inhibited by erythromycin in low concentrations such as 0.1〜0.5 μg/ml, but that of erythromycin resistant strain was not inhibited even by the presence of 1000 μg/ml of erythromycin. Evidence was presented indicating that erythromycin resistant Lactobacillus arabinosus 17-5 and Streptococcus faecalis R were available organisms for determination of pantothenic and folic acid respectively in the sample containing erythromycin, for example, in the urine which excreted after erythromycin doses.
日本ビタミン学会の論文