菌體成分に關する研究(第1報) : ペニシリン菌體中のステリンに就て

概要

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(1) Crystals of sterol (m.p.about 150°) were isolated from the mycelium of Penicillium phrysogenum Q-176 obtained from three "Penicillin" manufactories, with the maximum yield corresponding to 0.33% of the dried mycelium.(2) It was difficult to isolate pure ergosterol (m.p.162〜163°) by mere recrystallization of crude sterols, indicating that some other sterols are mixed.(3) Purified sterol (m.p.145°) gave in color reactions and elementary analysis the same results as pure ergosterol.(4) The isolated sterol crystalls (m. p. 148.5°, 153°, 155°) gave the same adsorption maximnm at 260,280,282 and 293 mμ as pure ergosterol, and by the calculatiou from absorption coefficient they seem to be almost pure ergosterol (nearly 100%).
社団法人日本生物工学会の論文
1949-09-15