混合ビタミン剤のマイクロバイオアッセー : (III)混合剤中のビタミンB_<12>の定量成績(2)

概要

論文の詳細を見る
Fourteen multiple-vitamin preparations, ten tablets and powders and four liquids, were assayed of their vitamin B_<12> activity. The method employed for microbiological determination is a modification of the U.S.P. XV procedure employing Lactobacillus leichmannii ATCC No 7830. The analytical data obtained hereof and the corresponding data obtained from the published reports are presented in Fig.1 and Fig.2. The vitamin activities found are expressed as percentages of the labeled potencies. As shown in these figures, tablets and capules show fairly satisfactory activities over 90% of all samples, and a few samples of 2-3 years old are found much below the labeled potencies. The lack of stability of vitamin B_<12> is particularly noticed in oral liquids.
日本ビタミン学会の論文