国産シリカゲルによる有機酸の定量

概要

論文の詳細を見る
The authours examined the possibility of applying a home-made silica gel (Kanto Kagaku Co.) to the separation and determination of the organic acids used in this experiment. The results obtained by developing 28 kinds of known organic acid on a home-made silica gel column with n-butanol-chloroform as solvent were compared with those obtained on Mallinkrodt silica gel column.1) The peak effuent volume of organic acids flowed out through 20gr. Mallinkrodt silica gel was the same as that did through 16gr. home-made silica gel.2) Though the effuent order and recovery of each of the organic acids were much the same in both the silica gels, the tailing was somewhat little in Mallinkrodt silica gel.3) The separation of pyruvic, fumaric and formic acids by both the silica gels was not good, and that of malonic, aconitic and pyroglutamic acids was also difficult.4) Recoveries of organic acids which flowed out through the silica gels with 100% chloroform and those of keto acids, such as pyruvic, α-ketoglutaric and oxalacetic acids, were low in each of the gels.5) Judging from the experimental results, the home-made silica gel seemed to the used satifactorily in the separation and determination of organic acids instead of Mallinkrodt silica gel.
1960-05-15