酵母の糖醗酵性遺伝に関する研究 : D-Galactoseの醗酵性について

概要

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Genetic surveys have been made of the haploid clones of Saccharomyces yeasts incapable of fermenting D-galactose in nutrient broth within two weeks. Based on the mating experiments with a number of haploid non-fermenters, these strains can be classified into three groups on the basis of complementary effects observed with heterozygous diploids derived therefrom; two of these groups comprise strains from among our laboratory stocks, and the other those derived from Carbondale breeding stocks.Tetrad analyses of haploid clones belonging to these three groups have revealed that the inability of these clones to ferment galactose is due to the deficiency in only one gene. Three recessive genes are postulated : ga_<AM> and ga_<KM>, which are found in clones from our laboratory stocks, behave as if they were closely linked together and do not show linkage to another gene, ga_<CA>, which has been derived from Carbondale stocks.The striking features of dihybrid with regard to ga_<AM> and ga_<KM> in trans-configuration is to ferment D-galactose after long-term adaptation which is not reversed to lose the ability by de-adaptation treatment.In view of the above results, the possibility of pseudoallelic relationship between ga_<AM> and ga_<KM> is discussed.
社団法人日本生物工学会の論文
1959-10-15