交流磁界曝露による線虫C. elegans hsp-16遺伝子への影響

概要

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The effect of ac electromagnetic fields (EMFs) was studied on the expression of the hsp-16-lacZ fusion gene in Caenorhabditis elegans. An alternating and a rotating EMFs at 60 Hz were compared under high-precision temperature control. The expression of the fusion gene was assessed by the extent of positive animals on lacZ after exposure to heat or heat-magnetic field stress. Expression of the fusion gene was enhanced when transgenic animals were exposed to an alternating EMF up to 0.5T. The expression was not detected in transgenic animals defective in the hsp promoter region. Thus, the enhancement of the fusion gene was dependent on the strength of the alternating EMFs. The significant induction of hsp-16 was also observed when animals was exposed to a rotating EMFs.
社団法人日本磁気学会の論文
2001-04-15