PE-447 Disruption of VEGF Signaling Pathway in Frontal Cortex of Juvenile Male SHRSP : Possible Implications for Cerebrovascular Abnormalities in Attention-Deficit/Hyperactivity Disorder(Cerebrovascular Circulation/Stroke 2 (H) : PE76)(Poster Session (Eng

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概要

• 論文の詳細を見る
• 社団法人日本循環器学会の論文
• 2004-03-01

著者

• Akioka Kaname

  大阪市立大学 医学部循環器病態内科学

• Sakuma Ichiro

  北海道大学 医学研究科循環病態内科学分野

• Sakuma Ichiro

  Dept. Of Pharmacology Hokkaido University Graduate School Of Medicine

• Subrina Jesmin

  Division Of Gene Therapeutics Research Institute International Medical Center Of Japan

• Subrina Jesmin

  Center For Tsukuba Advanced Research Alliance (tara) University Of Tsukuba

• Kitabatake Akira

  北海道大学 大学院医学研究科循環病態内科学

• Kitabatake A

  山口大学 医学系研究科器官病態内科学

• Togashi Hiroko

  北海道大学

• Yoshioka Mitsuhiro

  Facul.of Pharm.sci. Higashi-nippon-gakuen Univ. 1st Dept.of Pharmacol

• Kitabatake Akira

  Hokkaido University

• Jesmin Subrina

  Hokkaido University Graduate School of Medicine

• Sakuma Ichiro

  Hokkaido University Graduate School of Medicine

• Togashi Hiroko

  Hokkaido University Graduate School of Medicine

• Yoshioka Mitsuhiro

  Hokkaido University Graduate School of Medicine

• Akioka Kaname

  Osaka City University Medical School

• Mowa Chishimba

  Hokkaido University Graduate School of Medicine

• Ueno Ken-ichi

  Hokkaido University Graduate School of Medicine

• Yamaguchi Taku

  Hokkaido University Graduate School of Medicine

• Kitabatake Akira

  Hokkaido Univ. Sapporo Jpn

• Sakuma Ichiro

  Hokkaido University

• Togashi Hiroko

  1st Dept. Of Pharmacol. Hokkaido Univ. Sch. Of Med.

• Sakuma Ichiro

  Department Of Cardiovascular Medicine School Of Medicine Hokkaido University

• Yamaguchi Taku

  Department Of Neuropharmacology Hokkaido University Graduate School Of Medicine

• Jesmin Subrina

  Center For Tsukuba Advanced Research Alliance (tara) University Of Tsukuba:institute Of Clinical Med

• Yoshida Takayuki

  Department Of Neuropharmacology Hokkaido University Graduate School Of Medicine

• Sakuma Ichiro

  Univ. Tokyo

関連論文

• 1 Pharmacogenomics of β-blocker Therapy in Chronic Heart Failure(New Approaches to Heart Failure-from Pharmacogenomics to Drug Development, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Which is most Beneficial for Preserving Cardiac Function and Coronary Microvasculaturein DCM, ACE-I, ARB or Two in Combination? (Cardiac Hypertrophy/Cardiomyopathy 2 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Eplerenone Prevents Cardiac Fibrosis through the Inhibition of OPN Expression (Cardiac Hypertrophy, Basic (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Osteopontin is Essential for Angiotensin II-Induced Cardiac Fibrosis(Heart Failure, Basic 2 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Virtual Electrode-induced Spiral Reentry in Ventricular Myocardium Perfused in-vitro
• Dynamics of Functional Reentry in 2-Dimensional Ventricular Myocardium with Uniform Anisotropy : A High-Resolution Optical Mapping Analysis
• Na^+ Channel Blockade Causes a Prolongation of Electrical Diastole during Spiral-type Reentry in the Ventricle
• Preferential suppression of the longitudinal conduction by Na^+ channel blockade serves a substrate for spiral reentry in the ventricle
• PJ-500 Coronary Artery Affects the Wave Propagation in a Thin Ventricular Myocardium : Study by the Optical Mapping and Computer Graphics Techniques(Arrhythmia, Basic 6 (A) : PJ84)(Poster Session (Japanese))
• PJ-777 Role of Endothelin in the Impairment Cardiac Function, Cardiac VEGF Signaling and Coronary Collateral Development in Early Diabetic Rats(Diabetes/Obesity/Metabolic syndrome-12, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-776 Normalization of Cardiac Upregulated Endothelin-1 System in Type 2 Diabetic Rat by A Long-Acting Calcium Channel Blocker at Sub-Depressor Dose(Diabetes/Obesity/Metabolic syndrome-12, The 71st Annual Scientific Meeting of the Japanese Circulation So
• PJ-692 Endothelin Selective A Receptor Antagonist Recovers Downregulated VEGF, NO and BCL-2 Expression in Penile Tissues in Type 1 Diabetic Rat(Peripheral circulation/Vascular disease-7, The 71st Annual Scientific Meeting of the Japanese Circulation Socie
• PJ-573 Chronic Treatment with Endothelin Receptor Antagonist Normalizes the Altered Cerebral Capillary Density in the Frontal Cortex of SHR-SP Rats(Cerebrovascular circulation/Stroke-3, The 71st Annual Scientific Meeting of the Japanese Circulation Societ
• Virtual Electrode Polarization-Induced Reentrant Activity
• A high-resolution mapping and analysis system of action potentials during vortex-type arrhythmias
• DPE-020 Estrogen Receptor-α Plays Dominant Role in the Preservation of VEGF Signaling in Coronary Microcirculation in Heart of Female Mice(DPE04,Coronary Circulation/Chronic Coronary Disease (Basic/Clinical) (IHD),Digital Poster Session (English),The 73rd
• PE-611 Estrogen Receptor Alpha is More Actively Involved in the Cardiac VEGF/KDR/NO Pathway Compared to Estrogen Receptor Beta in Female Mice(Neurohumoral factors-2 (H) PE108,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the J
• PJ-022 Feasible and Accurate Measurement of Left Ventricular Volume and Ejection Fraction by New Real-Time Three-Dimensional Echocardiography(Echo/Doppler 2 (I) : PJ4)(Poster Session (Japanese))
• PE-010 Moderate Hypothermia Destabilized Spiral Waves without Widening Excitable Gap in Favor of Self-termination of Ventricular Tachycardia/Fibrillation(Arrhythmia, basic(03)(A),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese C
• PE-017 Moderate Hypothermia Causes Destabilization of Rotors without Wavelength Shortening in Favor of VT/VF Self-Termination(Arrhythmia, basic-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-149 Pacing-Induced Heart Failure in Rabbits Accelerates Subepicardial Ventricular Repolarization in Favor of Mother Rotor-Type Ventricular Fibrillation(Arrhythmia, basic-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PE-330 Concentration-dependent Modification of Spiral-wave Reentry by Verapamil in a Perfused 2-dimensional Layer of Rabbit Ventricular Myocardium(Arrhythmia, basic-4 (A) PE55,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the
• OE-238 Mechanisms of Global and Regional Cooling-Assisted Defibrillation in a Bidomain Ventricular Model(Arrhythmia, basic-1 (A) OE40,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• Acute Amiodarone Suppresses Action Potential Alternans in the Two-dimensional Ventricular Myocardium of Rabbit Hearts(Arrhythmia, Basic 4 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Action Potential Dynamics of Spiral-type Reentry in 2-Dimensional Anisotropic Layer of Ventricular Muscle : Optical Mapping Analysis Using High-fidelity CMOS Camera(Arrhythmia, Basic 3 (A), The 69th Annual Scientific Meeting of the Japanese Circulation So
• FRS-054 Bepridil Destabilizes Spiral-Wave Reentry in Favor of Its Early Termination through Tremendous Drift of Rotation Center(FRS11,New Insights into Basic Mechanisms of Arrhythmia (A),Featured Research Session (English),The 73rd Annual Scientific Meeti
• Evaluation of Effects of Polymorphism for Metabolic Enzymes on Pharmacokinetics of Carvedilol by Population Pharmacokinetic Analysis(Biopharmacy)
• OJ-426 Enhanced Temporal and Spatial Cycle Length Variability during Ventricular Fibrillation in Hypertrophic Cardiomyopathy(ECG/Body Surface Potential Mapping/Holter 6 (A) : OJ52)(Oral Presentation (Japanese))
• Hypofibrinolysis Downregulates Coronary Capillary Network Remodeling in Aged Obese Diabetic Rats : Implications for Increased Myocardial Vulnerability to Ischemia in Diabetes
• Novel Polyethylene Glycol Conjugated S-Nitrosylated Hemoglobin Potently Inhibits Platelet Activation and Adhesion to Artificial Surfaces : Therapeutic Implications for Platelet-Rich Thrombus
• Effects of hemoglobin derivatives on the liver microcirculation system ; evaluation of the s-nitroso-polyethylene glycol modified hemoglobin as an artificial oxygen carrier
• A Long-Acting Calcium Channel Blocker, Benidipine, Ameliorates Diabetic Cardiac Remodeling and Normalizes the Upregulated Endothelin-1 System in Diabetic Rat(Cardiovascular Pharmacology, Basic/Clinical 1 (H), The 69th Annual Scientific Meeting of the Japa
• Estrogen Receptor Alpha and Beta Are Equally Involved in Cerebral Vascular Endothelial Growth Factor/KDR/Nitric Oxide Pathway in Female Mice(Cerebrovascular Circulation/Stroke 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• PE-445 Long-term Endothelin Antagonism Reverses the Hypertension-induced Neurovascular Remodeling in the Frontal Cortex of SHR-SP(Cerebrovascular Circulation/Stroke 2 (H) : PE76)(Poster Session (English))
• OE-313 Reduced Activity and Expression of Matrix Metalloproteinase-2 and Membrane-Type-1-MMP in Coronary Matrix Remodeling in NIDDM Rat : Role of Angiotensin II(Diabetes/Obesity 2 (H) : OE40)(Oral Presentation (English))
• FRS-122 Endothelin-1 and its Signaling Pathway is Upregulated in a Type 2 Diabetic Rat Heart : Potential Reversal by Calcium Channel Antagonism(Metabolic Syndrome (H) : FRS15)(Featured Research Session (English))
• Hypofibrinolysis and Increased Metalloproteinase Expression Associated with Coronary Vasculopathy in NIDDM : Primary Role of Angiotensin II Type 1 Receptor
• Activation of Angiotensin II Type 1 Receptor with Angiotensin II Increases Coronary VEGF Expression via an AGEs-HIF-1α Pathway in NIDDM
• Estrogen Mediates Flow-Preserving Neurprotection via Its Angiogenic Action and Sustained NO Production in Middle-Aged Female Rat Brain
• Decrease in Estrogen by Aging Renders Myocardium Ischemic and Estrogen Replacement May Not Fully Protect Heart in Female Rats
• Microangiopathy with dysregulation of angiogenic and apoptotic factors in penile vascular tissues in diabetes mellitus
• PE-584 Plasma NT-proBNP Concentration is a Sensitive Marker of Diastolic Dysfunction and Arterial Remodeling in Hypertension(Hypertension, clinical-7 (H) PE102,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circula
• Usefulness of Left Parasternal Approach for the Continuous-Wave Doppler Measurement of Left Ventricular Outflow Tract Pressure Gradient in Patients With Hypertrophic Cardiomyopathy
• PJ-283 Early Detection of High Risk Patients for Atherosclerosis in Untreated Hypertensive Patients(Atherosclerosis, Clinical 3 (IHD) : PJ48)(Poster Session (Japanese))
• PJ-135 Feasibility of the Assessment of Left Ventricular Diastolic Function Using Doppler-Derived Early Diastolic Peak Strain Rate(Echo/Doppler 6 (I) : PJ23)(Poster Session (Japanese))
• PJ-020 Evaluation of Circumferential and Longitudinal Myocardial Contraction Using Tissue Doppler Strain Measurement in Patients with Generalized Left Ventricular Myocardial Impairment(Echo/Doppler 2 (I) : PJ4)(Poster Session (Japanese))
• PE-447 Disruption of VEGF Signaling Pathway in Frontal Cortex of Juvenile Male SHRSP : Possible Implications for Cerebrovascular Abnormalities in Attention-Deficit/Hyperactivity Disorder(Cerebrovascular Circulation/Stroke 2 (H) : PE76)(Poster Session (Eng
• Experimental Study of the Relationship between Perfluoro-Octyl Bromide Emulsion and Norepinephrine Release in Reperfusion Arrhythmia : Isolated Guinea Pig Heart Model
• PJ-270 Microbubble Destruction with Ultrasound Augments Neovascularization by Bone Marrow Cell Transplantation in Rat Hindlimb Ischemia(Peripheral circulation-7 (H) PJ46,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japan
• PE-617 Design and Preliminary Outcome of the Pravastatin or Atorvastatin Evaluation in Japan (PROVE-J) Trial(Preventive medicine/Epidemiology/Education-5 (H) PE109,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Cir
• PE-528 High Prevalence of Metabolic Abnormalities in Patients with Acute Myocardial Infarction in the Northern Regions of Japan During 2003-2005(Preventive medicine/Epidemiology/Education-3 (H) PE89,Poster Session (English),The 70th Anniversary Annual Sci
• Angiotensin converting enzyme inhibitors attenuated the expression of G-protein coupled receptor kinases in heart failure patients
• Chronic beta-adrenergic receptor stimulation enhances the expression of G-Protein coupled receptor kinases, GRK2 and GRK5, in both the heart and peripheral lymphocytes
• Myocardial Blood Volume Assessed by Contrast Echocardiography is Associated with Contractile Reserve in Patients with Idiopathic Dilated Cardiomyopathy(Echo/Doppler 7 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Effects of Cell Transplantation Using Vascular Endothelial Growth Factor-Expressing Mesenchymal Stem Cells for Myocardial Infarction(Acute Myocardial Infarction, Basic 1 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• CCAAT/enhancer Binding Protein δ is Critical for Induction of Plasminogen Activator Inhibitor-1 by Interleukin (IL)-1β and IL-6 in Hepatocytes(Infection/Inflammation/Immunity 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Long-Term Beneficial Effect of Infarct-Related Artery Patency in Acute Anterior Myocardial Infarction in Patients With Poor Myocardial Viability in the Region-at-Risk
• An S-Nitrosylated Hemoglobin Derivative Protects the Rat Hippocampus From Ischemia-Induced Long-Term Potentiation Impairment With a Time Window
• Detecting Viable Myocardium and Predicting Functional Improvement : Comparisons of Positron Emission Tomography, Rest-Redistribution Thallium-201 Single-Photon Emission Computed Tomography (SPECT), Exercise Thallium-201 Reinjection SPECT, I-123 BMIPP SPEC
• Granulocyte-Colony Stimulating Factor Augments Neovascularization Induced by Bone Marrow Transplantation in Rat Hindlimb Ischemia
• Angiotensin Blockade Inhibits Osteopontin Expression in Non-infarcted Myocardium After Myocardial Infarction
• OJ-070 Combined Effects of INa and ICa, Blockade on Spiral Wave Reentry in Perfused 2-dimensional Layer of Rabbit Ventricular Myocardium(Arrythmia, basic(02)(A),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Soc
• PJ-160 Comparative Analysis of Dual Actions of Nifekalant on I_(PJ027,Arrhythmia, Others (Clinical/Pathophysiology) 2 (A),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• Experimental Study of Pegylated Liposomal Hemoglobin on Norepinephrine Release and Reperfusion Arrhythmias in Isolated Guinea Pig Hearts
• FRS-058 An s-Nitrosylated Hemoglobin Derivative Improves Ischemia/Reperfusion-Induced Functional Damage and Remodeling of the Rat Brain(Oxidative Stress, Autonomic Function and Peripheral Vascular Diseases (H) : FRS7)(Featured Research Session (English))
• An s-Nitrosylated Hemoglobin Derivative Protects Rat Brain from Cerebral Ischemia
• VEGF, Its Receptors and Other Angiogenic Growth Factors Are Altered Potentially in an Age-Related Manner in SHRSP Heart
• OJ-392 A New Method to Measure Myocardial Strain along the Left Ventricular Circumference Using Tissue Doppler Echocardiography(Echo/Doppler 14 (I) : OJ48)(Oral Presentation (Japanese))
• PE-009 Acute amiodarone slows down the spiral rotation and prevents the wave-break during ventricular tachycardia(Arrhythmia, Basic 3 (A) : PE2)(Poster Session (English))
• PE-008 Effects of Nifekalant Hydrochrolide on the Spiral-type Functional Reentry in 2-Dimensional Rabbit Ventricular Myocardium(Arrhythmia, Basic 3 (A) : PE2)(Poster Session (English))
• OJ-173 Natural Killer T Cells and Perforin-Producing CD4T Cells are Diversely Activated in Stable Angina Versus Unstable Angina(Infection/Inflammation/Immunity 1 (H) : OJ20)(Oral Presentation (Japanese))
• Mechanisms of destabilization and early termination of spiral-wave reentry in the ventricle by a class III antiarrhythmic agent, nifekalant
• Upregulation of KCNE1 Induces QT Interval Prolongation in Patients With Chronic Heart Failure
• Computer Simulation Analysis of Shock Intensity - and Phase - Dependence of High-Intensity DC Stimulation Aftereffects on Action Potential of Ventricular Muscle
• PE-181 CCAAT-Enhancer Binding Protein Delta Mediates the Up-regulation of Plasminogen Activator Inhibitor-1 Induced by lnterleukin-6 and its Attenuation by Mevastatin(Infection/Inflammation/Immunity 2 (H) : PE31)(Poster Session (English))
• Effects of Aldosterone Receptor Antagonist and Angiotensin II Type I Receptor Blocker on Cardiac Transcriptional Factors and mRNA Expression in Rats With Myocardial Infarction
• DIPYRIDAMOLE POTENTIATES ANTIAGGREGATING AND VASORELAXING EFFECTS OF ENDOTHELIUM-DERIVED RELAXING FACTOR BY THE INHIBITION OF CYCLIC GMP PHOSPHODIESTERASE
• -1210-NEW EDRF-INHIBITORS AND THEIR PHARMACOLOGICAL PROPERTIES: COMPARISON WITH L-N^G-MONOMETHYLARGININE : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• -1209-POTENTIATION BY DIPYRIDAMOLE OF THE NITRIC OXIDE-INDUCED RELAXATION OF VASCULAR SMOOTH MUSCLES: THE ROLE OF DIPYRIDAMOLE AS A cGMP-PHOSPHODIESTERASE INHIBITOR : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• -1084-RELATION BETWEEN LEFT VENTRICULAR MASS AND CARDIAC ARRHYTHMIA IN HYPERTROPHIC CARDIOMYOPATHY : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• -1053-EFFECTS OF ENDOTHELIUM-DERIVED RELAXING FACTOR ON BLOOD PRESSURE AND CENTRAL AUTONOMIC NEVER CONTROL : AN ASSESSMENT USING L-N^G-MONO-METHYLARGININE : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• Effects of Isoproterenol on Ventricular Vulnerability
• A New Multi-Channel Optical System to Record Action Potentials from the Heart Perfused In-vitro
• Optical recording of action potentials from isolated rabbit hearts subjected to high-intensity DC field stimulation
• OJ-214 Differences in Cardiovascular Risk Factors of Coronary Artery Disease : A Study on Ethnic Differences in Subclinical Hypofibrinolysis and Inflammation(Blood Coagulation/Fibrinolysis (IHD) : OJ24)(Oral Presentation (Japanese))
• OJ-209 Hepatocyte Growth Factor Activates PAI-1 Production in Human Liver Cells Through the MEK and Tyrosine Kinase-dependent Signaling Pathways(Blood Coagulation/Fibrinolysis (IHD) : OJ24)(Oral Presentation (Japanese))
• A Dynamic Action Potential Model Analysis of Shock-Induced Aftereffects in Ventricular Muscle by Reversible Breakdown of Cell Membrane
• [SHORT REPORTS]Effects of Low-Intensity Field Stimulation on Action Potential Repolarization and Refractory Period in Guinea Pig Ventricular Muscle: The Influence of Electrical Axis with Respect of Fiber Orientation
• [SHORT REPORTS]Effects of Countershock-Type Field Stimulation on the Electro-Mechanical Properties of Guinea Pig Verntricular Muscles:VI. Influence of the Electrical Axis of Stimulation
• PJ-279 The Effects of Azithromycin Therapy on the Coronary Microcirculation in Patients With Coronary Artery Disease Assessed by Transthoracic Doppler Echocardiography(Infection/Inflammation/Immunity 3 (H) : PJ47)(Poster Session (Japanese))
• -0938-ANGIOTENSIN II STIMULATES PROTEIN SYNTHESIS IN CARDIAC FIBROBLASTS OF CARDIOMYOPATHIC HAMSTERS : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• OJ-190 Macrophage Specific Overexpression of Allograft Inflammatory Factor-1 in Transgenic Mice Promotes Phagocytotic Activity Following Thioglycollate Stimulation and Regulate Atherosclerotic Progression(Atherosclerosis, Basic 2 (IHD) : OJ22)(Oral Presen
• Wire-Induced Myocardial Ischemia : A Novel Approach to Create Myocardial Ischemia in Rats
• Experimental Studies on Artificial Blood Usage for Hemodilution during Cardiopulmonary Bypass
• Prognostic Significance of Left Ventricular Diastolic Dysfunction Assessed by Color M-mode Doppler Echocardiography in Patients With Chronic Left Ventricular Systolic Dysfunction
• Therapeutic Potentials of an Artificial Oxygen-Carrier, Liposome-Encapsulated Hemoglobin, for Ischemia/Reperfusion-Induced Cerebral Dysfunction in Rats
• PJ-619 Hydrostatic Pressure Induces Cardiomyocyte Hypertrophy via Calcineurin/NFAT Signaling Pathway(Cardiac Hypertrophy, Basic and Clinical 2 (M) : PJ104)(Poster Session (Japanese))
• Bepridil Facilitates Early Termination of Spiral-Wave Reentry in Two-Dimensional Cardiac Muscle Through an Increase of Intercellular Electrical Coupling
• Low HDL-cholesterol, hypertension and impaired glucose tolerance as predictors of acute myocardial infarction in northern area of Japan
• Pharmacological Blockade of I_ Destabilizes Spiral-Wave Reentry Under β-Adrenergic Stimulation in Favor of Its Early Termination

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