Experimental Study of Pegylated Liposomal Hemoglobin on Norepinephrine Release and Reperfusion Arrhythmias in Isolated Guinea Pig Hearts

スポンサーリンク

概要

• 論文の詳細を見る
• 2007-12-01

著者

• Sakuma Ichiro

  北海道大学 医学研究科循環病態内科学分野

• Sakuma Ichiro

  Department Of Cardiovascular Medicine Hokkaido University School Of Medicine

• Sakuma Ichiro

  Dept. Of Pharmacology Hokkaido University Graduate School Of Medicine

• SHIIYA NORIHIKO

  Department of Cardiovascular Surgery, Hokkaido University School of Medicine

• YASUDA KEISHU

  Department of Cardiovascular Surgery, Hokkaido University School of Medicine

• Sakuma Ichiro

  名古屋大学環境医学研究所

• OGATA Yoshitaka

  Terumo Corporation Research and Development Center

• ISHIZUKA Takanobu

  Terumo Corporation Research and Development Center

• Sakuma Ichiro

  Hokkaido University Graduate School of Medicine

• ISAKA Mitsuhiro

  Department of Thoracic and Cardiovascular Surgery, Hiroshima Prefectural Hospital

• IMAMURA Michiaki

  Arkansas Children's Hospital, Pediatric Cardiac Surgery

• Isaka Mitsuhiro

  Department Of Cardiovascular Surgery Hokkaido University School Of Medicine

• Sakuma Ichiro

  Department Of Cardiovascular Medicine Graduate School Of Medicine Hokkaido University

• Yasuda Keishu

  Pediatric Cardiac Surgery Arkansas Children's Hospital

• Yasuda Keishu

  Department Of Cardiovascular Surgery Hokkaido University

• Shiiya Norihiko

  Department Of Cardiovascular Surgery Hokkaido University Hospital

• Shiiya Norihiko

  Department Of Cardiovascular Surgery Hokkaido University School Of Medicine

• Ogata Yoshitaka

  Terumo Co. Ltd.

• Ogata Yoshitaka

  Terumo Corporation

• Ishizuka Takanobu

  Terumo Corporation

• Imamura Michiaki

  Arkansas Children's Hospital Pediatric Cardiac Surgery

• Yasuda Keishu

  Department At Cardiovascular Surgery Hohkaido University School Of Medicine

関連論文

• Virtual Electrode-induced Spiral Reentry in Ventricular Myocardium Perfused in-vitro
• Dynamics of Functional Reentry in 2-Dimensional Ventricular Myocardium with Uniform Anisotropy : A High-Resolution Optical Mapping Analysis
• Na^+ Channel Blockade Causes a Prolongation of Electrical Diastole during Spiral-type Reentry in the Ventricle
• Preferential suppression of the longitudinal conduction by Na^+ channel blockade serves a substrate for spiral reentry in the ventricle
• PJ-500 Coronary Artery Affects the Wave Propagation in a Thin Ventricular Myocardium : Study by the Optical Mapping and Computer Graphics Techniques(Arrhythmia, Basic 6 (A) : PJ84)(Poster Session (Japanese))
• PJ-776 Normalization of Cardiac Upregulated Endothelin-1 System in Type 2 Diabetic Rat by A Long-Acting Calcium Channel Blocker at Sub-Depressor Dose(Diabetes/Obesity/Metabolic syndrome-12, The 71st Annual Scientific Meeting of the Japanese Circulation So
• Virtual Electrode Polarization-Induced Reentrant Activity
• A high-resolution mapping and analysis system of action potentials during vortex-type arrhythmias
• DPE-020 Estrogen Receptor-α Plays Dominant Role in the Preservation of VEGF Signaling in Coronary Microcirculation in Heart of Female Mice(DPE04,Coronary Circulation/Chronic Coronary Disease (Basic/Clinical) (IHD),Digital Poster Session (English),The 73rd
• PE-611 Estrogen Receptor Alpha is More Actively Involved in the Cardiac VEGF/KDR/NO Pathway Compared to Estrogen Receptor Beta in Female Mice(Neurohumoral factors-2 (H) PE108,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the J
• Therapeutic Potentials of an Artificial Oxygen-Carrier, Liposome-Encapsulated Hemoglobin, for Ischemia/Reperfusion-Induced Cerebral Dysfunction in Rats
• Close Correlation between Cytoplasmic Ca^ Levels and Release of an Endothelium - Derived Relaxing Factor from Cultured Endothelial Cells
• PE-010 Moderate Hypothermia Destabilized Spiral Waves without Widening Excitable Gap in Favor of Self-termination of Ventricular Tachycardia/Fibrillation(Arrhythmia, basic(03)(A),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese C
• PE-017 Moderate Hypothermia Causes Destabilization of Rotors without Wavelength Shortening in Favor of VT/VF Self-Termination(Arrhythmia, basic-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-149 Pacing-Induced Heart Failure in Rabbits Accelerates Subepicardial Ventricular Repolarization in Favor of Mother Rotor-Type Ventricular Fibrillation(Arrhythmia, basic-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PE-330 Concentration-dependent Modification of Spiral-wave Reentry by Verapamil in a Perfused 2-dimensional Layer of Rabbit Ventricular Myocardium(Arrhythmia, basic-4 (A) PE55,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the
• OE-238 Mechanisms of Global and Regional Cooling-Assisted Defibrillation in a Bidomain Ventricular Model(Arrhythmia, basic-1 (A) OE40,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• Acute Amiodarone Suppresses Action Potential Alternans in the Two-dimensional Ventricular Myocardium of Rabbit Hearts(Arrhythmia, Basic 4 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Action Potential Dynamics of Spiral-type Reentry in 2-Dimensional Anisotropic Layer of Ventricular Muscle : Optical Mapping Analysis Using High-fidelity CMOS Camera(Arrhythmia, Basic 3 (A), The 69th Annual Scientific Meeting of the Japanese Circulation So
• FRS-054 Bepridil Destabilizes Spiral-Wave Reentry in Favor of Its Early Termination through Tremendous Drift of Rotation Center(FRS11,New Insights into Basic Mechanisms of Arrhythmia (A),Featured Research Session (English),The 73rd Annual Scientific Meeti
• Hypofibrinolysis Downregulates Coronary Capillary Network Remodeling in Aged Obese Diabetic Rats : Implications for Increased Myocardial Vulnerability to Ischemia in Diabetes
• Novel Polyethylene Glycol Conjugated S-Nitrosylated Hemoglobin Potently Inhibits Platelet Activation and Adhesion to Artificial Surfaces : Therapeutic Implications for Platelet-Rich Thrombus
• Effects of hemoglobin derivatives on the liver microcirculation system ; evaluation of the s-nitroso-polyethylene glycol modified hemoglobin as an artificial oxygen carrier
• Effects of Angiotensin-Converting Enzyme Inhibition and Angiotensin II Type 1 Receptor Blockade on β-Adrenoceptor Signaling in Heart Failure
• Estrogen Upregulates Acetylcholine-lnduced EDHF-Mediated Relaxation via Connexin43, Whereas Inhibits EDRF-Mediated One in the Female Rat Mesenteric Artery
• HDL-Cholesterol is an Important Predictor of Coronary Artery Disease among middle-Aged Men : 10-Year Follow-Up of Cohort of 6146 White-color Workers (Preventive Medicine/Epidemiology/Education/Health Policy 6 (H), The 69th Annual Scientific Meeting of the
• Simvastatin Improves Endothelial Function Due to Its Effects on Lipids and Pleiotropic Effects in Patients With Chronic Hemodialysis(Lipid Disorders 4 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Molecular and Functional Characterization of a Novel Regulator of Carnitine Transporter OCTN2(Metabolism/Biochemistry/Energetics 1 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• A Long-Acting Calcium Channel Blocker, Benidipine, Ameliorates Diabetic Cardiac Remodeling and Normalizes the Upregulated Endothelin-1 System in Diabetic Rat(Cardiovascular Pharmacology, Basic/Clinical 1 (H), The 69th Annual Scientific Meeting of the Japa
• Estrogen Receptor Alpha and Beta Are Equally Involved in Cerebral Vascular Endothelial Growth Factor/KDR/Nitric Oxide Pathway in Female Mice(Cerebrovascular Circulation/Stroke 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• PE-445 Long-term Endothelin Antagonism Reverses the Hypertension-induced Neurovascular Remodeling in the Frontal Cortex of SHR-SP(Cerebrovascular Circulation/Stroke 2 (H) : PE76)(Poster Session (English))
• OE-313 Reduced Activity and Expression of Matrix Metalloproteinase-2 and Membrane-Type-1-MMP in Coronary Matrix Remodeling in NIDDM Rat : Role of Angiotensin II(Diabetes/Obesity 2 (H) : OE40)(Oral Presentation (English))
• FRS-122 Endothelin-1 and its Signaling Pathway is Upregulated in a Type 2 Diabetic Rat Heart : Potential Reversal by Calcium Channel Antagonism(Metabolic Syndrome (H) : FRS15)(Featured Research Session (English))
• Hypofibrinolysis and Increased Metalloproteinase Expression Associated with Coronary Vasculopathy in NIDDM : Primary Role of Angiotensin II Type 1 Receptor
• Activation of Angiotensin II Type 1 Receptor with Angiotensin II Increases Coronary VEGF Expression via an AGEs-HIF-1α Pathway in NIDDM
• Estrogen Mediates Flow-Preserving Neurprotection via Its Angiogenic Action and Sustained NO Production in Middle-Aged Female Rat Brain
• Decrease in Estrogen by Aging Renders Myocardium Ischemic and Estrogen Replacement May Not Fully Protect Heart in Female Rats
• Microangiopathy with dysregulation of angiogenic and apoptotic factors in penile vascular tissues in diabetes mellitus
• Regulation of microvascular angiogenesis by estrogen in the heart of middle-aged female rats
• Differential distribution of angiotensin II receptors in coronary microvasculature in diabetic heart : the potential clinical significance
• PE-447 Disruption of VEGF Signaling Pathway in Frontal Cortex of Juvenile Male SHRSP : Possible Implications for Cerebrovascular Abnormalities in Attention-Deficit/Hyperactivity Disorder(Cerebrovascular Circulation/Stroke 2 (H) : PE76)(Poster Session (Eng
• Experimental Study of the Relationship between Perfluoro-Octyl Bromide Emulsion and Norepinephrine Release in Reperfusion Arrhythmia : Isolated Guinea Pig Heart Model
• An S-Nitrosylated Hemoglobin Derivative Protects the Rat Hippocampus From Ischemia-Induced Long-Term Potentiation Impairment With a Time Window
• OJ-070 Combined Effects of INa and ICa, Blockade on Spiral Wave Reentry in Perfused 2-dimensional Layer of Rabbit Ventricular Myocardium(Arrythmia, basic(02)(A),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Soc
• PJ-160 Comparative Analysis of Dual Actions of Nifekalant on I_(PJ027,Arrhythmia, Others (Clinical/Pathophysiology) 2 (A),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• OJ-178 Simvastatin Prevents Thrombotic Occlusion of Arterio-Venous Shunt in Dialysis Patients And Improves Endothelial Function Due to Its Pleiotropic Effects(Peripheral Circulation/Vascular Disease 1 (H) : OJ21)(Oral Presentation (Japanese))
• Experimental Study of Pegylated Liposomal Hemoglobin on Norepinephrine Release and Reperfusion Arrhythmias in Isolated Guinea Pig Hearts
• FRS-058 An s-Nitrosylated Hemoglobin Derivative Improves Ischemia/Reperfusion-Induced Functional Damage and Remodeling of the Rat Brain(Oxidative Stress, Autonomic Function and Peripheral Vascular Diseases (H) : FRS7)(Featured Research Session (English))
• An s-Nitrosylated Hemoglobin Derivative Protects Rat Brain from Cerebral Ischemia
• VEGF, Its Receptors and Other Angiogenic Growth Factors Are Altered Potentially in an Age-Related Manner in SHRSP Heart
• OJ-035 Masked Obesity in Young Women Manifest With Deteriorated Metabolic Indices and They Are Reversed by Regular Exercise Practice(Diabetes/Obesity 1 (H) : OJ5)(Oral Presentation (Japanese))
• PE-009 Acute amiodarone slows down the spiral rotation and prevents the wave-break during ventricular tachycardia(Arrhythmia, Basic 3 (A) : PE2)(Poster Session (English))
• PE-008 Effects of Nifekalant Hydrochrolide on the Spiral-type Functional Reentry in 2-Dimensional Rabbit Ventricular Myocardium(Arrhythmia, Basic 3 (A) : PE2)(Poster Session (English))
• Menopause and Cardiovascular Diseases in Women
• Men's Health Study : Epidemiology of Erectile Dysfunction and Cardiovascular Disease
• Mechanisms of destabilization and early termination of spiral-wave reentry in the ventricle by a class III antiarrhythmic agent, nifekalant
• Upregulation of KCNE1 Induces QT Interval Prolongation in Patients With Chronic Heart Failure
• Computer Simulation Analysis of Shock Intensity - and Phase - Dependence of High-Intensity DC Stimulation Aftereffects on Action Potential of Ventricular Muscle
• -112-DECREASE OF FINGER TEMPERATURE (FIT) DURING EXERCISE AS A FUNCTION OF THE INDIVIDUAL MAXIMAL POINT
• DIPYRIDAMOLE POTENTIATES ANTIAGGREGATING AND VASORELAXING EFFECTS OF ENDOTHELIUM-DERIVED RELAXING FACTOR BY THE INHIBITION OF CYCLIC GMP PHOSPHODIESTERASE
• -1210-NEW EDRF-INHIBITORS AND THEIR PHARMACOLOGICAL PROPERTIES: COMPARISON WITH L-N^G-MONOMETHYLARGININE : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• -1209-POTENTIATION BY DIPYRIDAMOLE OF THE NITRIC OXIDE-INDUCED RELAXATION OF VASCULAR SMOOTH MUSCLES: THE ROLE OF DIPYRIDAMOLE AS A cGMP-PHOSPHODIESTERASE INHIBITOR : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• -1084-RELATION BETWEEN LEFT VENTRICULAR MASS AND CARDIAC ARRHYTHMIA IN HYPERTROPHIC CARDIOMYOPATHY : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• -1053-EFFECTS OF ENDOTHELIUM-DERIVED RELAXING FACTOR ON BLOOD PRESSURE AND CENTRAL AUTONOMIC NEVER CONTROL : AN ASSESSMENT USING L-N^G-MONO-METHYLARGININE : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• -0803-ANTI-AGGREGATING ACTION OF ENDOTHELIUMDERIVED RELAXING FACTOR (EDRF) : ITS EFFECTS ON INTRAPLATELET Ca^ MOBILIZATION AND MODIFICATION BY DILTIAZEM (DTZ)
• -0791-MECHANISM FOR THE GENERATION OF ENDOTHELIUM-DERIVED RELAXING FACTOR BY α_2-STMULATION
• -0607-ANTI-AGGREGATING MECHANISMS OF EDRF IN HUMAN PLATELETS : EFFECTS OF EDRF ON THROMBIN-INDUCED IP_3 PRODUCTION AND CA^ MOBILIZATION
• -0566-THE IN VIVO MEASUREMENT OF THE MYOCARDIAL INTERSTITIAL POTASSIUM AND LACTATE CONCENTRATIONS IN THE BEATING CANINE HEART USING AN IMPROVED MICRODIALSIS TECHNIQUE
• -0130-THE INFLUENCE OF ANEMIA AND LATENT IRON DEFICIENCY ON EXERCISE CAPACITY AND THE EFFECT OF IRON ADMINISTRATION : STUDY WITH EXPIRATORY GAS ANALYSIS
• -0094-ENDOTHELIUM-DERIVED RELAXING FACTOR RELEASED FROM HUMAN INTERNAL MAMMARY ARTERY : ITS IDENTIFICATION AS NITRIC OXIDE AND EFFECTS OF SURGICAL MANEUVERS AT BYPASS OPERATION ON ITS RELEA
• THE MECHANISM OF ENDOTHELIUM-DERIVED RELAXING FACTOR RELEASE IN GUINEA PIG MAIN PULMONARY ARTERY : AN ASSESSMENT USING N^G-MONOMETHYL L-ARGININE : Pulmonary, Peripheral, Cerebral Circulation : 53 Annual Scientific Meeting, Japanese Circulation Society
• VASOACTIVE ACTION OF PEPTIDOLEUKOTRIENES ON GUINEA PIG MAIN PULMONARY ARTERY : MODIFICATION BY AN ENDOTHELIUM-DERIVED RELAXING FACTOR : Pulmonary, Peripheral, Cerebral Circulation : 53 Annual Scientific Meeting, Japanese Circulation Society
• DIPYRIDAMOLE POTENTIATES EDRF-MEDIATED INHIBITION OF PLATELET AGGREGATION : THE ROLE OF DIPYRIDAMOLE IN VIVO AS A CYCLIC GMP PHOSPHODIESTERASE INHIBITOR : Myocardial Metabolism, Biochemistry : 53 Annual Scientific Meeting, Japanese Circulation Society
• POSITIVE INOTROPIC EFFECT OF HISTAMINE ON GUINEA PIG LEFT ATRIUM : H1-RECEPTOR-INDUCED STIMULATION OF PHOSPHOINOSITIDE TURNOVER : Myocardial Metabolism, Biochemistry : 53 Annual Scientific Meeting, Japanese Circulation Society
• THE THROMBOXANE ANALOG U-46619 INDUCES POSITIVE INOTROPIC EFFECT IN GUINEA PIG LEFT ATRIUM : AN ASSOCIATION WITH AN INCREASED PHOSPHOINOSITIDE METABOLISM : Cardiovascular Drugs : 53 Annual Scientific Meeting, Japanese Circulation Society
• A NEW SUBCLASSIFICATION OF APICAL HYPERTROPHIC CARDIOMYOPATHY BASED ON LEFT VENTRLICULAR MASS : APICAL HYPERTROPHY WITH TRIVIAL LEFT VENTRICULAR HYPERTROPHY : Cardiomyopathy (II) : PROCEEDINGS OF THE 50th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULAT
• EVALUATION OF THE CARDIAC MUSCLE HYPERTROPHIC PATTERNS IN PATIENTS WITH HYPERTROPHIC CARDIOMYOPATHY (HCM) BY USE OF MULTI-SLICE SERIAL ECG-GATED CARDIAC COMPUTED TOMOGRAPHY (MSECT) : Doppler, RI : I : 48 Annual Scientific Meeting, Japanese Circulation Soc
• EVALUATION OF LEFT VENTRICULAR MASS (LVM) BY MULTI-SLICE SERIAL ECG-GATED CARDIAC X-RAY COMPUTED TOMOGRAPHY (MSECT) : PROCEEDINGS OF THE 47th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY : Computerized Tomography
• 12) EVALUATION OF LEFT VENTRICULAR MASS IN PATIENTS WITH IDIOPATHIC CARDIOMYOPATHY BY MULTI-SLICE SERIAL ECG-GATED CARDIAC X-RAY COMPUTED TOMOGRAPHY (MSECT)
• Effects of Isoproterenol on Ventricular Vulnerability
• A New Multi-Channel Optical System to Record Action Potentials from the Heart Perfused In-vitro
• Optical recording of action potentials from isolated rabbit hearts subjected to high-intensity DC field stimulation
• A Rice Diet Is Associated with Less Fat Synthesis/Accumulation than a Bread Diet before Exercise Therapy
• A Dynamic Action Potential Model Analysis of Shock-Induced Aftereffects in Ventricular Muscle by Reversible Breakdown of Cell Membrane
• [SHORT REPORTS]Effects of Low-Intensity Field Stimulation on Action Potential Repolarization and Refractory Period in Guinea Pig Ventricular Muscle: The Influence of Electrical Axis with Respect of Fiber Orientation
• [SHORT REPORTS]Effects of Countershock-Type Field Stimulation on the Electro-Mechanical Properties of Guinea Pig Verntricular Muscles:VI. Influence of the Electrical Axis of Stimulation
• EVALUATION OF BI-VENTRICULAR FUNCTION USING MULTI-SLICE SERIAL ECG-GATED COMPUTED TOMOGRAPHY : Ventricular Function : 46th Annual Scientific Meeting, Japanese Circulation Society
• 16) EVALUATION OF CARDIAC STRUCTURE AND BI-VENTRICULAR FUNCTION IN PATIENTS WITH IDIOPATHIC CARDIOMYOPATHY BY MULTI-SLICE SERIAL ECG-GATED COMPUTED TOMOGRAPHY
• 10) EVALUATION OF CARDIAC STRUCTURE AND DYNAMIC FUNCTION IN PATIENTS WITH IDIOPATHIC CARDIOMYOPATHY BY ECG-GATED COMPUTED TOMOGRAPHY (PRELIMINARY REPORT)
• -0938-ANGIOTENSIN II STIMULATES PROTEIN SYNTHESIS IN CARDIAC FIBROBLASTS OF CARDIOMYOPATHIC HAMSTERS : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• -0512-ANGIOTENSIN II POTENTIATES EXTRACELLULAR MATRIX PRODUCTION IN THE MYOCARDIUM OF SPONTANEOUSLY HYPERTENSIVE RATS
• -0029-ANALYSIS OF AMOUNT, TYPES AND REDUCIBLE CROSSLINKS OF CARDIOMYOPATHIC (BIO 14.6) AND NORMAL(FIB) HAMSTERS
• Experimental Studies on Artificial Blood Usage for Hemodilution during Cardiopulmonary Bypass
• Pregnancy and Cardiovascular Disease(Morning Lecture 6 (ML6) (H))(Special Program)
• Is HRT Effective for Prevention of Cardiovascular Diseases?(The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Gender Difference in Risk Factors for Acute Myocardial Infarction in Japan(Gender-specific Meidicine in Cardiovascular Disease, The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• A Visualization Study to Evaluate the Relationship between Flow Pattern and the Impeller Vane Configuration
• Therapeutic Potentials of an Artificial Oxygen-Carrier, Liposome-Encapsulated Hemoglobin, for Ischemia/Reperfusion-Induced Cerebral Dysfunction in Rats
• Bepridil Facilitates Early Termination of Spiral-Wave Reentry in Two-Dimensional Cardiac Muscle Through an Increase of Intercellular Electrical Coupling
• Pharmacological Blockade of I_ Destabilizes Spiral-Wave Reentry Under β-Adrenergic Stimulation in Favor of Its Early Termination

もっと見る 閉じる

スポンサーリンク