Synthesis of Hydroxymethylglutathione from Glutathione and L-Serine Catalyzed by Carboxypeptidase Y(Biochemistry & Molecular Biology)

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概要

• 論文の詳細を見る

• Hydroxymethylglutathione (γ-L-glutamyl-L-cysteinyl-L-serine ; hmGSH) occurs in many species belonging to the family Gramineae, but the biosynthetic pathway for hmGSH has not been identified. We found that carboxypeptidase Y (CPY), but not carboxypeptidase A, catalyzed hmGSH synthesis from glutathione and L-serine in vitro at acidic pH. CPY also catalyzed methyl-glutathione synthesis from glutathione and L-alanine. These findings suggested that a carboxypeptidase-like enzyme may be involved in hmGSH synthesis in vivo.

• 社団法人日本農芸化学会の論文
• 2003-02-23

著者

• Koizumi Yukio

  Division Of Applied Life Sciences Graduate School Of Agriculture Kyoto University

• Sekiya Jiro

  Division Of Applied Life Sciences Graduate School Of Agriculture Kyoto University

• Sekiya Jiro

  Division Of Applied Life Sciences Graduate School Of Agricultural Sciences Kyoto University

• OKUMURA Ryosuke

  Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University

• Okumura Ryosuke

  Division Of Applied Life Sciences Graduate School Of Agriculture Kyoto University

関連論文

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• Synthesis of Hydroxymethylglutathione from Glutathione and L-Serine Catalyzed by Carboxypeptidase Y(Biochemistry & Molecular Biology)
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• Purification and Properties of Soluble and Bound γ-Glutamyltransferases from Radish Cotyledon
• Laser Microdissection in Combination with Microarray-Based Gene Expression Analysis
• Purification and Characterization of Dipeptidase Hydrolyzing L-Cysteinylglycine from Radish Cotyledon

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