Synthesis and Fungicidal Activity of 1- (α-tert-Butylcinnamoyl) imidazoles(Organic Chemistry)

概要

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Several 1- (α-tert-butylcinnamoyl) imidazoles were prepared to examine their fungicidal activity. The (Z) -4-chlorocinnamoyl derivative was prepared from (anti) -2-tert-butyl-3- (4-chlorophenyl) -3-hydroxypropanoic acid by treating with 1, 1'-carbonyldiimidazole and a subsequent β-elimination reaction at an elevated temperature. The (Z) -isomer of the 4-chlorocinnamoyl derivative showed good f ungicidal activity against Erysiphe graminis and Botrytis cinerea in pot tests, whereas the corresponding (E) -isomer derived from the (Z) -isomer through photoisomerization was much less active.
社団法人日本農芸化学会の論文
2002-10-23