Production of cis-1, 2-Dihydroxy-3-Methylcyclohexa-3, 5-Diene (Toluene cis Glycol) by Rhodococcus sp. MA 7249
スポンサーリンク
概要
- 論文の詳細を見る
An attractive method for producing cis-1, 2-dihydroxy-3-methylcyclohexa-3, 5-diene (toluene cis glycol) was developed employing a cis dihydrodiol dehydrogenase "deficient" strain of Rhodococcus (MA 7249). The toluene cis glycol produced was found to have optical rotations of [α]_D^<25>=+25.8 (c 0.45, CH_3OH) and +72.8 (c 0.42, CHCl_3) which indicated an absolute configuration of (LS, 2R) when compared with previously published values. When cultivated in laboratory fermentor in the presence of toluene vapors, MA 7249 reached a toluene cis glycol concentration up to 18 g/l in 110 h. Calture MA 7249 also accumulated cis (LS, 2R) dihydrodiols from dihydronaphthalene, biphenyl, chlorobenzene, and styrene.
- 社団法人日本生物工学会の論文
- 2000-09-25
著者
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Chartrain M
Merck Res. Lab. Nj Usa
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Taylor Colleen
Department Of Bioprocess Merck Research Laboratories
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Greasham R
Merck Res. Lab. Nj Usa
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CHARTRAIN MICHEL
Department of Bioprocess, Merck Research Laboratories
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IKEMOTO NORIHIRO
Process Research, Merck Research Laboratories
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STAHL SARAH
Department of Bioprocess, Merck Research Laboratories
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SANDFORD VANESSA
Department of Bioprocess, Merck Research Laboratories
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GBEWONYO KODZO
Department of Bioprocess, Merck Research Laboratories
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CHIRDO CHRISTINE
Department of Bioprocess, Merck Research Laboratories
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MAXWELL CARRIE
Department of Bioprocess, Merck Research Laboratories
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OSORIA JERELYN
Department of Bioprocess, Merck Research Laboratories
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BUCKLAND BARRY
Department of Bioprocess, Merck Research Laboratories
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GREASHAM RANDOLPH
Department of Bioprocess, Merck Research Laboratories
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Stahl Sarah
Department Of Bioprocess R&d Merck Research Laboratories
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Buckland Barry
Department Of Bioprocess Merck Research Laboratories
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Osoria Jerelyn
Department Of Bioprocess Merck Research Laboratories
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Gbewonyo Kodzo
Department Of Bioprocess Merck Research Laboratories
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Chartrain Michel
Department Of Bioprocess R&d And Department Of Process Research Merck Research Labortories
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Sandford Vanessa
Department Of Bioprocess Merck Research Laboratories
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Chirdo Christine
Department Of Bioprocess Merck Research Laboratories
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Ikemoto Norihiro
Process Research Merck Research Laboratories
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Greasham Randolph
Department Of Bioprocess R&d And Department Of Process Research Merck Research Labortories
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