血液凝固・線溶に及ぼす運動の影響

概要

論文の詳細を見る
The effects of exercise on the blood coagulation system, fibrinolytic system and peripheral blood cell components were examined. Eleven normal healthy subjects (male, 22±1 yr) were studied under three conditions: maximum, 80% VO_<2max> and 60% VO_<2max> exercise on a bicycle ergometer. The blood was collected before, immediafely after exercise, and at 1. and 2hrs. after exercise. In the maximum exercise group, fibrin formation was suspected. No evidence of fibrinolysis was observed, which is due to increase in both the fibrinolytic activator system and fibrinolytic inhibitory system. In the 80% VO_<2max> exercise group, fibrinolysis was accelerated with and increase in t-PA and decrease in PAI-1. On the other hand, peripheral blood findings showed hemoconcentration and a significant increase in platelets. These findings indicate that 80% VO_<2max> exercise is not appropriate exercise intensity. In the 60% VO_2<2max> exercise group, t-PA was significantly increased and PAI-1 continuously decreased. That is, fibrinolytic activator system was activated and fibrinolytic inhibitory system was repressed in this group. These findings suggested that 60% VO_<2max> exercise was safe and had a moderate effect on blood coagulation and fibrinolysis.
日本運動生理学会の論文
1996-08-31