Effect of Preinfarction Angina on Heart Rate Variability in the Early Phase of the First Anterior Wall Acute Myocardial Infarction

概要

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The aim of this study was to clarify the effect of preinfarction angina on heart rate variability (HRV) in anterior wall acute myocardial infarction (AMI). A total of 36 patients experiencing their first anterior wall AMI were prospectively examined. The patients were divided into 2 groups according to the presence (group A, n=24) or absence (group B, n=12) of preinfarction angina. HRV was assessed on 24-h Holter electrocardiograms recorded on day 3. Peak creatine kinase activity was significantly lower in group A than in group B (2,747±1,939 vs 4,891±2,639 IU/L, p<0.05). The SD of all RR intervals and ultra-low frequency, very low frequency, and low frequency powers was significantly less reduced in group A than in group B (86±24 vs 64±22ms, p<0.05; 2,098±1,462 vs 867±502ms^2, p<0.01; 1,430±1,042 vs 546±344ms^2 p<0.01; and 354±272 vs 186±136ms^2 p<0.05; respectively). High frequency power, low frequency/high frequency, and pNN50 did not differ significantly between the 2 groups. In conclusion, preinfarction angina has a favorable influence on HRV in the early phase of anterior wall AMI.
社団法人日本循環器学会の論文
2002-04-20