Industrial Production of D-Aspartic Acid and L-Alanine from DL-Aspartic Acid Using a Pressurized Column Reactor Containing Immobilized Pseudomonas dacunhae Cells
スポンサーリンク
概要
- 論文の詳細を見る
The simultaneous production of D-sapartic acid and L-alanine from DL-aspartic acid has been investigated by using a pressurized column reactor containing immobilized Pseudomonas dacunhae cells. The L-aspartate β-decarboxylase of P. dacunhae cells was inhibited by D-aspartic acid. The enzyme activity of the immobilized P. dacunhae cell in the pressurized column reactor decayed exponentially during operation, and its half-life was approximately 96 d at 37℃. D-Aspartic acid and L-alanine were crystallized out in good yield by acidification and concentration of the reactor effluent. This novel bioreactor system was industrialized in 1988.
- 社団法人日本生物工学会の論文
- 1989-04-25
著者
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Tosa Tetsuya
Research Laboratory of Applied Biochemistry, Tanabe Seiyaku Co., Ltd.
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Tosa Tetsuya
Research Laboratory Of Applied Biochemistry Tanabe Seiyaku Co. Ltd.
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SENUMA MASARU
Research Laboratory of Applied Biochemistry, Tanabe Seiyaku Co. Ltd.,
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OTUKI OSAMU
Research Laboratory of Applied Biochemistry, Tanabe Seiyaku Co. Ltd.,
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SAKATA NOBUYUKI
Research Laboratory of Applied Biochemistry, Tanabe Seiyaku Co. Ltd.,
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FURUI MASAKATSU
Research Laboratory of Applied Biochemistry, Tanabe Seiyaku Co. Ltd.,
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Otuki Osamu
Research Laboratory Of Applied Biochemistry Tanabe Seiyaku Co. Ltd.
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Senuma Masaru
Research Laboratory Of Applied Biochemistry Tanabe Seiyaku Co. Ltd.
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Sakata Nobuyuki
Research Laboratory Of Applied Biochemistry Tanabe Seiyaku Co. Ltd.
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Furui Masakatsu
Research Laboratory Of Applied Biochemistry Tanabe Seiyaku Co. Ltd.
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- Industrial Production of D-Aspartic Acid and L-Alanine from DL-Aspartic Acid Using a Pressurized Column Reactor Containing Immobilized Pseudomonas dacunhae Cells
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