A Novel Splicing Isoform of Mouse Sterol Regulatory Element-binding Protein-1 (SREBP-1)
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概要
- 論文の詳細を見る
We cloned a cDNA encoding the NH_2-terminal portion of mouse SREBP-1. The deduced amino acid sequence was 76% and 90% identical to human and hamster SREBP-1,respectively. We found out a novel splicing isoform of mouse SREBP-1 that lacks 42 amino acid residues composing a PEST sequence observed in unstable proteins. It has been reported that SREBP-1 is rapidly turned over in the nucleus. Although this isoform was not a dominant isoform, it might be possible that the produced protein functions differently from other isoforms including a complete PEST sequence.
- 社団法人日本農芸化学会の論文
- 1999-01-23
著者
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Sato Ryuichiro
Dep. Of Applied Biological Chemistry Graduate School Of Agriculture And Life Sciences Univ. Of Tokyo
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Sato Ryuichiro
Laboratory Of Biochemistry And Molecular Biology Graduate School Of Pharmaceutical Sciences Osaka Un
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Sato R
Department Of Applied Biological Chemistry The University Of Tokyo
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INOUE Jun
Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka
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Sato Ryuichiro
Laboratory Of Biochemistry And Molecular Biology Graduate School Of Pharmaceutical Sciences Osaka Un
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Inoue Jun
Laboratory Of Biochemistry And Molecular Biology Graduate School Of Pharmaceutical Sciences Osaka Un
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