Unique Inhibition of Miltpain, a New Cysteine Proteinase from the Milt of Chum Salmon, by o-Phenanthroline, Phenanthrenequinone, Phenazine, and Acridine
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概要
- 論文の詳細を見る
Miltpain (EC 3.4.22.-) is a new cysteine proteinase that has been isolated from the milt of chum salmon (Oncorhynchus keta), and is strongly inhibited by cysteine proteinase inhibitors such as E-64, iodoacetamide, NEM, and PCMB. This paper deals with a unique feature, that the enzyme becomes inhibited by o-phenanthroline, phenanthrenequinone, phenanthrene, phenazine, and acridine which have some structural resemblance to a hydrophobic planar shape. Dixon plots showed that the inhibitions of the enzyme by o-phenanthroline and phenanthrenequinone were noncompetitive.
- 社団法人日本農芸化学会の論文
- 1997-08-23
著者
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Ichishima Eiji
Laboratory Of Enzymology And Microbial Chemistry Tokyo Noko University
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Ichishima Eiji
Laboratory Of Molecular Enzymology Department Of Applied Biological Chemistry Faculty Of Agriculture
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Kawabata Choko
Technical Research Center Of T. Hasegawa Co. Ltd.
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