Effect of reperfusion by direct percutaneous transluminal coronary angioplasty on ventricular late potentials in cases of total coronary occlusion at initial coronary arteriography

概要

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The relationship between the time required for reperfusion and the incidence of late potentials was studied in 94 patients who survived a first acute myocardial infarction (AMI) and who showed total occlusion of the infarct-related artery at an initial coronary arteriography. Sixty-three patients who successfully underwent direct percutaneous transluminal coronary angioplasty (PTCA), and 31 who were treated conventionally (controls), underwent signal-averaged electrocardiography. Direct PTCA patients were classified into 5 groups according to the time required for reperfusion: ⪇ 4, 4-6, 6-8, 8-10, and ⪈ 10 h. The incidence of late potentials in these groups was 8%, 12%, 14%, 33%, and 43%, respectively, and 48% in the controls. Late potentials were recorded more frequently as the period until successful reperfusion increased: the incidence of late potentials was significantly lower in the ⪇4 and 4-6 h groups than in the controls (p < 0.005 and p< 0.05, respectively). Therefore, reperfusion achieved within 6h reduced the incidence of late potentials in AMI patients and may be effective for preventing malignant ventricular arrhythmias.
社団法人日本循環器学会の論文
1993-03-20