A QUANTITATIVE ANALYSIS OF RESERVOIR FUNCTION OF THE HUMAN PULMONARY "VENOUS" SYSTEM FOR THE LEFT VENTRICLE

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概要

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• By definition, the pulmonary "venous" system consists of the pulmonary veins and the left atrium. The stiffness of the pulmonary "venous" (P'V') system and the left ventricle (LV) at the end of the slow filling period (at the point of pre-a) were estimated sequentially in a total of 26 patients, divided into a control group and mitral stenosis (MS), angina pectoris (AP), hypertrophic cardiomyopathy (HCM) groups. The stiffness (ΔP/ΔV) of the P'V' system was estimated from the pulmonary artery wedge (PAW) pressure tracings and the stroke volume. The stiffness (dP/dV) of LV was obtained from the pressure-volume (P-V) relationship of LV with a model of P = be^<aV>. The present study is aimed primarily at obtaining factual information. The stiffness of the P'V'system was 0.063 ± 0.022 mmHg/ml (mean ± SD) in the control group and 0.052 ± 0.006 mmHg/ml in the HCM group (p > 0.1). The stiffness of LV in diastole was 0.091 ± 0.016 mmHg/ml in the control group and 0.199 ± 0.056 mmHg/ml in the HCM group (p < 0.01). The ratio of the stiffness of LV in diastole to that of the P'V' system was 1.6 ± 0.6 in the control group and 3.8 ± 0.7 in the HCM group. The volume elastic constant (a) of the P'V' system was 0.008 ± 0.005 ml^<-1> in the control group and the values of (a) occupied a range of 0.007 to 0.008 ml^<-1> in the remaining 3 groups of patients. The values of (a) of LV were 0.011 ± 0.004 ml^<-1> in the control group and 0.022 ± 0.007 ml^<-1> in the HCM group (p < 0.01). The present study suggests that the P'V' system is usually 2 to 3 times more compliant than LV in diastole. On the other hand, the P'V' system remained compliant in spite of the decreased compliance of LV in diastole in the HCM group, maintaining the reservoir function with which pulmonary edema is prevented.

• 社団法人日本循環器学会の論文
• 1986-03-20

著者

• Suzuki Takahiko

  Toyohashi Heart Center

• Hirose Isao

  The Second Department Of Internal Medicine Gifu University School Of Medicine

• TANAKA Tsutomu

  Second Department of Internal Medicine, Gifu University School of Medicine

• Gotoh Masahiro

  The Second Department Of Internal Medicine Gifu University School Of Medicine

• Ito Hiroyasu

  The 2nd Department Of Internal Medicine Gifu University School Of Medicine

• Yamaguchi Masato

  2nd Dept Of Int Med Gifu Univ

• Goto M

  Kyushu Univ. Fukuoka Jpn

• Suzuki Takahiko

  2nd Department Of Internal Medicine Gifu University

• Yamaguchi Masato

  The Second Department of Internal Medicine, School of Medicine, Kanazawa University, Kanazawa

• Miyamoto Hiromichi

  The Second Department Of Internal Medicine Gifu University School Of Medicine

• ARAKAWA MICHIO

  The Second Department of Internal Medicine, Gifu University School of Medicine

• TANAKA TSUTOMU

  The Second Department of Internal Medicine, Gifu University School of Medicine

• TAKAYA TADATAKE

  The Second Department of Internal Medicine, Gifu University School of Medicine

• HIRAKAWA SENRI

  The Second Department of Internal Medicine, Gifu University School of Medicine

• GOTO MASAHIRO

  The Second Department of Internal Medicine, Gifu University School of Medicine

• SUZUKI TAKAHIKO

  The Second Department of Internal Medicine, Gifu University School of Medicine

• ITO HIROYASU

  The Second Department of Internal Medicine, Gifu University School of Medicine

• Ito Hiroyasu

  The 2^<nd> Department Of Internal Medicine Gifu University School Of Medicine

• Miwa Hiroshi

  Second Department Of Internal Medicine Gifu University School Of Medicine

• Tanaka Tsutomu

  The 2nd Dept. Of Intern. Med. Gifu Univ. School Of Med. Gifu

• Goto Masahiro

  The Second Department Of Internal Medicine Gifu University School Of Medicine

• Arakawa Micho

  2nd Dept Of Int Med Gifu Univ

• Arakawa Michio

  Second Department Of Internal Medicine Gifu University School Of Medicine

• Arakawa Michio

  Gifu University School Of Medicine

• Hirakawa Senri

  The Second Department Of Internal Medicine Gifu University School Of Medicine

• Tanaka Tsutomu

  Second Department Of Internal Medicine Gifu University School Of Medicine

• Takaya Tadatake

  Second Department Of Internal Medicine Gifu University School Of Medicine

• Miwa Hiroshi

  The Second Department of Internal Medicine Gifu university School of Medicine

• Suzuki Takahiko

  The Second Department Of Internal Medicine Gifu University School Of Medicine

• Ito Hiroyasu

  The Second Department Of Internal. Medicine Gifu University School Of Medicine

• Arakawa Michio

  Second Department Of Internal Medicine Gifu University School Of Medicine.

• Yamaguchi Masato

  Second Department Of Internal Medicine Gifu University School Of Medicine

• Tanaka Tsutomu

  The Second Department Of Internal Medicine Gifu University School Of Medicine

• Suzuki Takehiko

  Toyohashi Heart Center

• Hirakawa Senri

  2nd. Dept. Of Intern. Med Gifu Univ. School Of Med

• Arakawa Michio

  The Second Department Of Internal Medicine Gifu University School Of Medicine

• Yamaguchi Masato.

  Second Department Of Internal Medicine Gifu University School Of Medicine

• Hirakawa Senri

  岐阜大学 第2内科

• Takaya Tadatake

  2nd Dept Of Int Med Gifu Univ

• Yamaguchi Masato

  The Second Department Of Internal Medicine Gifu University School Of Medicine

• Arakawa Michio

  2nd Dept Of Int Med Gifu Univ

• Arakawa Michio

  岐阜大学 第2内科

• Hirakawa Senri

  Second Department Of Internal Medicine Gifu University School Of Medicine.

• Suzuki Takehiko

  The 2nd Department Of Lnternal Medicine Gifu University School Of Medicine

• Ito Hiroyasu

  The Second Department Of Internal Medicine Gifu University School Of Medicine

• Hirakawa Senri

  The 2 Depart. Of Intern. Med. Gifu Univesity Of Med.

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