REDUCED CHRONOTROPIC RESERVE TO THE METABOLIC REQUIREMENT DURING EXERCISE IN ADVANCED HEART FAILURE WITH OLD MYOCARDIAL INFARCTION
スポンサーリンク
概要
- 論文の詳細を見る
Westudiedthemetabolicandcardiacresponsestoexercisebyexpiratorygasanalysisin40patientswitholdmyocardialinfarctionand33normalsedentarymales.Onthebasisofexerciseenergymetabolism,theelevationoftherespiratoryquotient(RQ;RQ=VCO2/VO2)duringexerciseiscausedbytheincreaseofbloodlactateduetotheaugmentedanaerobicmetabolism.Functionalaerobicimpairment(FAI)inourstudywassignificantlyadvancedinthecontrolgroupandtheNYHAfunctionalclassI,classIIandclassIIIgroups,thatis,2.3±11.2%,+14.8±10.4%,+27.8±13.8%and+49.4±2.8%respectively.TheRQvaluesweresimilaramongallgroups;0.29±0.09respectively.Functionalchronotropicimpairment(FCI)forthesamegroupswas0.9±7.0%,+1.4±6.1%,+3.8±4.8%and+8.7±6.0%,andthatoftheclassIIIgroupwassignificantlylargerthanthatofthecontrolgroup.Thus,intheclassIIIcongestiveheartfailuregroup,thechronotropicresponsetothemetabolicrequirementwasimpairedincomparisontothecontrolgroup.ItwasconcludedthatthereducedchronotropicreservewaspresentinNYHAclassIIIpatientswitholdmyocardialinfarction,andthatthismechanismmightcontributetoadecreaseinthepumpreserveoftheheart,resultinginfurtherimpairmentofphysicalcapacityinthesepatients.
- 社団法人日本循環器学会の論文
- 1987-03-20
著者
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Yamabe Hiroshi
First Department of Internal medicine, Kobe University School of Medicine
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Kobayashi Katsuya
The First Department of Internal Medicine, Kobe University School of Medicine
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Fukuzaki Hisashi
The First Department Of Internal Medicine Kobe University School Of Medicine
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Kobayashi Katsuya
The First Department Of Internal Medicine Kobe University School Of Medicine
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Yamabe Hiroshi
The First Department Of Internal Medicine Kobe University School Of Medicine
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Yamabe H
Kobe Univ. School Of Medicine
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Takata Teruo
The First Department of Internal Medicine, Kobe University School of Medicine
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Fukuzaki Hisashi
The First Department Of Internal Medicine Kobe University
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Takata Teruo
The Department Of Internal Medicine Kobe Rosai Hospital
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Takata Teruo
The First Department Of Internal Medicine Kobe University School Of Medicine
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Kobayashi K
The First Department Of Internal Medicine Kobe University School Of Medicine
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Kobayashi Katzuya
Dept Of Intern Med. Div. I Kobe Univ. School Of Med.
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Yoshida Hiroyuki
The First Department Of Internal Medicine Kobe University School Of Medicine
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