Endomyocardial Biopsy Approach to the Patients with Ventricular Tachycardia with Special Reference to Arrhythmogenic Right Ventricular Dysplasia : SYMPOSIUM ON VENTRICULAR ARRHYTHMIA : BASIC AND CLINICAL STUDIES : 50th Annual Scientific Session of the Jap
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概要
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Right ventricular endomyocardial biopsies were performed in patients with repetitive ventricular tachycardia (VT; 8 patients) or ventricular premature beats (1 patient) which showed left bundle branch block morphology in electrocardiograms. These 9 males patients ranging in age from 21-55 years (mean 37.7 years) revealed enlargement and/or asynergy of the right ventricle in the ventriculogram. Randomly selected biopsied patients with dilated cardiomyopathy (DCM; 18 patients) and chronic right ventricular overloading (14 patients) who did not show the above-described arrhythmias served as controls. A histopathological analysis revealed advanced myocardal interstitial fibrosis associated with an increase in fatty tissue in 8 of the 9 patients (89%). Moreover, advanced hypertrophy of myocytes (grades 2 or more of our criteria), disarrangement of muscle bundles and endocardial thickening were prominent with incidences of 75%, 75% and 78%, respectively. Incidence of all findings was more pronounced in the ARVD group. suggestiveness of post-myocarditic change in the biopsied specimen was high in 1 patient, showing a lower incidence (12%) than the DCM group (17%). From these results, we can conclude that different etiological factors may be the based of these pathological changes. We believe that the presence of a large amount of fatty tissue within the myocardial tissue is an important element in the etiology of ventricular arrhythmias as it has also been recognized in patients with non-ARVD idopathic ventricular tachycardia in our biopsy series.
- 社団法人日本循環器学会の論文
- 1987-02-20
著者
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Hasumi Motonari
Department Of Radiology & Cardiology Tokyo Women's Medical College The 1st Department Of Me
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Hiroe Michiaki
Department of Nephrology and Cardiology, International Medical Center of Japan
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Hirosawa Koshichiro
Department Of Cardiovascular Surgery The Heart Institute Of Japan Tokyo Women's Medical Univers
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Morimoto Shin-ichiro
First Department Of Internal Medicine Shinshu University
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Sekiguchi Morie
Department of Cardiology and Radiology and Department of Internal Medicine, Tokyo Women's Medical Co
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KASANIKI HIROSHI
Department of Cardiology, The Heart Institute of Japan
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Hasumi Motonari
The Heart Institute Of Japan
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Hiroe Michiaki
Department Of Cardiology International Medical Center Of Japan
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Hirosawa Koshichiro
Department Of Cardiology Heart Institute Of Japan Tokyo Women's Medical College
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Hiroe Michiaki
Second Department Of Internal Medicine Tokyo Medical And Dental University
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Kasanuki Hiroshi
Department Of Cardiovascular Surgery Heart Institute Tokyo Women's Medical University
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Hasumi Motonari
Department Of Radiology Cardilogy & Cardiovascular Surgery Tokyo Women's Medical College &a
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Kurosawa Hiromi
Department Of Surgery The Heart Institute Of Japan Tokyo Women's Medical College
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Hasumi Motonari
Departments Of Cardiology Tokyo Women's Medical College
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Sekiguchi Morie
International Cardiomyopathy Study Section Japan Research Promotion Society For Cardiovascular Disea
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Sekiguchi Morie
International Cardiomyopathy Study Section Japan Research Promotion Society For Cardiovascular Disea
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