Microvascular Angina in a Patient With Aortic Stenosis

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概要

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• A 39-year-old woman had exercise-induced ST segment depression associated with chest pain. Cardiac evaluation revealed moderate aortic stenosis(AS), related to the bicuspid valves, with an aortic mean pressure gradient of 22 mmHg, a calculated aortic valve area of 1.3cm^2 and normal left ventricular(LV)peak systolic and end-diastolic pressures, but no LV hypertrophy, resulting in normal LV wall stress. Although the coronary arteries were angiographically normal, rapid atrial pacing and an intracoronary papaverine injection revealed a significantly decreased coronary flow reserve(CFR), which may have played an important role in the pathogenesis of angina pectoris in this patient. Though the CFR is usually decreased in patients with AS, as well as in microvascular angina, in this particular case, it appeared to have decreased as a consequence of microvascular dysfunction rather than of AS-related mechanisms.

• 社団法人日本循環器学会の論文
• 2001-08-20

著者

• Date Haruhiko

  First Department of Internal Medicine, University of Miyazaki

• Imamura Takuroh

  First Department of Internal Medicine, University of Miyazaki

• Eto T

  Circulatory And Body Fluid Regulation Faculty Of Medicine University Of Miyazaki

• Eto Tanenao

  First Department Of Internal Medicine Faculty Of Medicine University Of Miyazaki

• Nagoshi Toshiro

  First Department of Internal Medicine, Miyazaki Medical College, University of Miyazaki

• Kawamoto Riichirou

  First Department of Internal Medicine, University of Miyazaki, University of Miyazaki

• Ishikawa Tetsunori

  First Department of Internal Medicine, University of Miyazaki, University of Miyazaki

• Imamura Takuroh

  Department Of Internal Medicine Circulatory And Body Fluid Regulation University Of Miyazaki

• Nagoshi Toshiro

  First Department Of Internal Medicine Miyazaki Medical College University Of Miyazaki

• Date Haruhiko

  1st Department Of Internal Medicine Miyazaki University

• Takenaga Makoto

  Department Of Internal Medicine Miyazaki Social Insurance Hospital

• Matsuo Takeshi

  First Department of Internal Medicine, University of Miyazaki

• Matsuyama Akihiko

  First Department of Internal Medicine, Miyazaki Medical College

• Ishikawa Tetsunori

  Department Of Internal Medicine Miyazaki Social Insurance Hospital

• Koiwaya Yasushi

  First Department of Internal Medicine, Miyazaki Medical College

• KOIWAYA Yasushi

  宮崎医科大学 第一内科

• Koiwaya Yasushi

  First Department Of Internal Medicine Miyazaki Medical College

• Fujiura Yoshitake

  First Department of Internal Medicine, Miyazaki Medical College

• Maeno Masakazu

  First Department of Internal Medicine, Miyazaki Medical College

• Maeno Masakazu

  First Department Of Internal Medicine Miyazaki Medical College

• Eto Tanenao

  First Department Of Internal Medicine Department Of Pathology Miyazaki Medical College

• Kawabata Kuniasa

  First Department of Internal Medicine, Miyazaki Medical College

• Kawamoto Riichirou

  1st Department Of Internal Medicine Miyazaki University

• Matsuo Takeshi

  Department Of Internal Medicine Miyazaki Social Insurance Hospital

• Imamura Takuroh

  First Department Of Internal Medicine University Of Miyazaki

• Fujiura Yoshitake

  First Department Of Internal Medicine Miyazaki Medical College

• Kawabata Kuniasa

  First Department Of Internal Medicine Miyazaki Medical College

• Matsuo Takeshi

  First Department of Internal Medicine, Miyazaki Medical College

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