Heterogeneity of Myocardial Fluoro-18 2-Deoxyglucose Uptake in Patients With Apical Hypertrophic Cardiomyopathy

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概要

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• We have shown that myocardial glucose metabolism is heterogeneous in patients with hypertrophic cardiomyopathy. It is not known, however, whether glucose metabolism is impaired in patients with apical hypertrophic cardiomyopathy, which is fairly common in Japan. We studied 7 patients with apical hypertrophic cardiomyopathy and 5 normal subjects using fluoro-18 2-deoxyglucose (FDG) and positron emission tomography (PET). We calculated regional FDG fractional uptake and the inter-regional coefficient of variation (CV) of FDG fractional uptake in the interventricular septal, anteroapical, and posterolateral regions. The regional FDG fractional uptake was similar in the 2 groups and among the 3 different segments within each group. However, the inter-regional CV of FDG fractional uptake was increased in the anteroapical wall segment of the patient group compared with the control group and also with the other 2 regions in the patient group. The results did not differ when we studied another 5 patients and 6 normal control subjects with a PET scanner with higher spatial resolution. These data suggest that myocardial glucose metabolism may be impaired in the anteroapical wall segment of patients with apical hypertrophic cardiomyopathy.

• 社団法人日本循環器学会の論文
• 1997-02-20

著者

• Ikeda Jun

  Sendai Red Cross Hospital

• IDO Tatsuo

  Cyclotron Radioisotope Center, Tohoku University

• Ikeda Jun

  First department of Internal Medicine, Tohoku University School of Medicine

• Shirato Kunio

  First department of Internal Medicine, Tohoku University School of Medicine

• Yamane Yuriko

  First Department of Internal Medicine, Tohoku University, School of Medicine

• Ishide Nobumasa

  First Department of Internal Medicine, Tohoku University, School of Medicine

• Ishide Nobumasa

  Miyagi Study Group of Acute Myocardial Infarction(Miyagi-Ken Shinkin Kousoku Taisaku Kyogikai)

• Shiba Nobuyuki

  Department Of Cardiovascular Medicine Tohoku University Graduate School Of Medicine

• Yamane Yuriko

  Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine

• Kagaya Yutaka

  First Department of Internal Medicine, Tohoku University School of Medicine

• Chida Masanobu

  First Department of Internal Medicine, Tohoku University School of Medicine

• OTANI Hiroki

  First Division, Department of Anatomy, Shimane Medical University

• Shirato Kunio

  First Department Of Internal Medicine Tohoku University School Of Medicine

• Otani Hiroki

  First Division Department Of Anatomy Shimane Medical University

• Yamane Yuriko

  Department Of Cardiovascular Medicine Tohoku University Graduate School Of Medicine

• Chida Masanobu

  Department Of Cardiovascular Medicine Tohoku University Graduate School Of Medicine

• Takeyama Daiya

  The First Department Of Internal Medicine Tohoku University School Of Medicine

• Ido Tatsuo

  Cyclotron And Radioisotope Center Tohoku University

• Ishide Nobumasa

  The 1st.department Of Internal Medicine Tohoku University School Of Medicine

• Shiba Nobuyuki

  First Department of Internal Medicine, Tohoku University School of Medicine

• Takeyama Daiya

  First Department of Internal Medicine, Tohoku University School of Medicine

• Ishida Nobumasa

  The First Department Of Internal Medicine Tohoku University School Of Medicine

• Ikeda Jun

  The Department Of Cardiovascular Medicine Tohoku University Graduate School Of Medicine

• Ikeda Jun

  First Department Of Internal Medicine Tohoku University School Of Medicine

• Ishide Nobumasa

  東北大学

• Shiba Nobuyuki

  Departments Of Cardiovascular Medicine And Evidence-based Cardiovascular Medicine Tohoku University

• Shiba Nobuyuki

  Departments Of Cardiovascular Medicine And Evidence-based Cardiovascular Medicine Tohoku University

• Ishide Nobumasa

  First Department Of Internal Medicine Tohoku University School Of Medicine

• Shiba Nobuyuki

  Departments Of Cardiovascular Medicine And Evidence-based Cardiovascular Medicine Tohoku University

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