Differences in heavy-ion-induced DNA double-strand breaks in a mouse DNA repair-deficient mutant cell line (SL3-147) before and after chromatin proteolysis
スポンサーリンク
概要
- 論文の詳細を見る
DNA double-strand breaks induced by X- or neon beam-irradiation in a DNA double-strand break-repair-deficient mutant cell line (SL3-147) were examined. The increase in the number of DNA double-strand breaks was dose depend after irradiation with X-rays and neon beams and was enhanced by chromatin-proteolysis treatment before irradiation. These results suggest that the induction of DNA double-strand breaks by ionizing radiation, including heavy-ions, is influenced by the chromatin structure.
- 日本放射線影響学会の論文
著者
-
村上 正弘
放射線医学総合研究所
-
Eguchi-kasai Kiyomi
放射線医学総合研究所障害基礎研究部
-
Eguchi-kasai Kiyomi
放射線医学総合研究所
-
KANAI Tatsuaki
Division of Accelerator Physics and Engineering, National Institute of Radiological Sciences
-
Kanai Tatsuaki
Division Of Accelerator Physics And Engineering National Institute Of Radiological Sciences
-
SATO KOKI
放射線医学総合研究所障害基礎研究部
-
MINOHARA SHINICHI
Division of Accelerator Physics and Engineering, National Institute of Radiological Sciences
-
YATAGAT FUMIO
Institute of Physical and Chemical Research
-
Minohara Shinichi
Division Of Accelerator Physics And Engineering National Institute Of Radiological Sciences
-
Sato Koki
放射線医学総合研究所
-
Kanai T
Division Of Accelerator Physics And Engineering National Institute Of Radiological Sciences
関連論文
- Experimental Study ot Heavy Ion Radialion using Monkcy and Phantom
- Qualitative and quantitative difference in mutation induction between carbon- and neon-ion beams in normal human cells
- ネオンイオン線照射による染色体異常の原子間力顕微鏡による解析
- A Proton Dose Calculation Code for Treatment Planning Based on the Pencil Beam Algorithm
- Analysis of the Penumbra for Uniform Irradiation Fields Delivered by a Wobbler method
- The isoeffect dose of carbon ions depends on LET and fractionation
- 原子間力顕微鏡によるDNA損傷の検出 : 第28回大会シンポジウム : II.新しい変異原検出法へのアプローチ
- 原子間力顕微鏡によるDNA損傷の検出
- Differences in heavy-ion-induced DNA double-strand breaks in a mouse DNA repair-deficient mutant cell line (SL3-147) before and after chromatin proteolysis
- Wide View-Angle Imaging Obtained by Compounding Multidirection Images through a Narrow Window
- The Relationship Between Tissue Damages and Radioprotective Actions of Tungstate
- Radioprotective Effects of Sodium Tungstate on Hematopoietic Injury by Exposure to ^Coγ-rays in Wistar Rats
- Protective Effects of Sodium Tungstate on ^Co γ-irradiation Induced Injury in Rats
- Chromosomal Aberrations in an Ionizing Radiation-Sensitive Mouse Lymphoma Mutant Cells Exposed to γ-rays and 4-Nitroquinoline-1-oxide
- Identification of a New G-to-A Transition Mutation at Nucleotide Position 129 of the Xrcc4 Gene in Ionizing Radiation-hypersensitive Mutant LX830 Cells
- Identification of the mutated gene in the ionizing radiation sensitive mutant M10 of mouse L5178Y cells
- Molecular characterization of ionizing radiation-hypersensitive mutant LX830 cells
- Interspecific Complementation between Mouse and Chinese Hamster Cell Mutants Hypersensitive to Ionizing Radiation
- Irradiation System for HIMAC
- Comparison of Mutability to X-Rays at Aprt and Hprt Loci between DNA-PKcs Deficient and Normal Cells
- Depth-Dose Distributions of High-Energy Carbon, Oxygen and Neon Beams in Water