Single- and Double-strand Breaks in pBR322 DNA by Vacuum-UV from 8.3 to 20.7 eV

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概要

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• Solid pBR322 DNA was irradiated in a vacuum by monochromatic photons from 8.3 eV (150 nm) to 20.7 eV (60 nm), and the formation of single- and double-strand breaks (ssb and dsb) was determined using agarose gel electrophoresis. The action cross sections increased 20 times (ssb) and 43 times (dsb) from 8.3 eV to 20.7 eV; the quantum yields increased 5.4 times (ssb) and 12 times (dsb). The cross sections for dsb were 0.0059 at 8.3 eV and 0.013 at 20.7 eV of those of ssb; these values were smaller than about 0.04 for 2.1 keV photons, or about 0.18 for ^<60>Co γ-rays. Although vacuum UV photons were proved to induce dsb, they had a lower efficiency than when using soft X-rays or γ-rays.

• 日本放射線影響学会の論文

著者

• Furusawa Yoshiya

  Research Center For Charged Particle Therapy National Institute Of Radiological Sciences

• Hirono Taisuke

  立教大学理学部生物物理学研究室

• SUZUKI MASAO

  Division of Radiation Biology, School of Medicine, Yokohama City University

• SUZUKI KEIJI

  立教大学理学部生物物理学研究室

• Suzuki Masao

  Division Of Radiation Hazards National Institute Of Radiological Sciences

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