Radiation Sensitivity of Human Bone Marrow Fibroblast Colony Forming Unit (CFU-F) to Various Radiation Sources

概要

論文の詳細を見る
The effects of 60 cobalt gamma rays (^<60>Co), tritiated water (HTO) beta rays and 252 californium (^<252>Cf) neutrons on stromal stem cells (CFU-F) from human fresh bone marrow were studied using an in vitro cell culture technique. Based on the survival curves of CFU-F, the D0 values of ^<60>Co, HTO and ^<252>Cf were 124 ± 30, 92 ± 12 and 60 ± 11 rad, respectively. From the D0values of ^<60>Co gamma rays, the relative biological effectiveness (RBE) of HTO beta rays and ^<252>Cf neutrons were calculated to be 1.3 and 2.1. However, due to the difference in the survival curves with or without initial shoulder, the RBEs of HTO and ^<252>Cf were dependent on the range of radiation dose. Both RBEs became higher than 3 in the low dose range of radiation (under 100 rad).
日本放射線影響学会の論文