Antimutagenic Activities of Human Placental Extract on Ultraviolet Light- and Gamma-Ray-Induced Mutation in Eseherichia coli WP 2 B/r trp

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概要

• 論文の詳細を見る

• Human placental extracts worked as a strong antimutagen on ultraviolet light (UV)- and - gamma-ray-induced mutations in Escherichia coli WP2 B/r trp. A number of antimutagenic factors has been known (see Clarke and Shankel, 1975 for review). It is of our interest to know whether human cells possess factors antagonizing with radiation-induced cellular mutagenesis. We previously reported that cobaltous chloride, a biometal compound, works as an antimutagen in radiation and chemically induced as well as spontaneous mutations in bacteria. We report here that the human placental extract is working as a strong antimutagen in UV- and gamma-ray-induced mutagenesis in bacteria.

• 日本放射線影響学会の論文

著者

• 賀田 恒夫

  国立遺伝学研究所

• 望月 肇

  国立遺伝学研究所変異遺伝部

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• 食べ合わせ現代考
• 青果物ジュースのニトロソジメチルアミン生成抑制
• レモンジュ-スによるニトロソモルホリンの生成抑制効果
• 調理と変異原性物質
• ライフサイエンスのための新体系(分子・微生物)遺伝学--遺伝子の構造・進化・修復
• Restorative Effects of Human Placenta Extract in X-Ray-Irradiated Mice
• Efficiencies of DNA Inactivation and Mutation Induction by Tritiated glycerol in Bacterial Systems
• Antimutagenic Activities of Human Placental Extract on Ultraviolet Light- and Gamma-Ray-Induced Mutation in Eseherichia coli WP 2 B/r trp
• 化学物質の遺伝毒性に関する本
• ライフサイエンスのための新体系(分子・微生物)遺伝学--外来DNAの細胞内取込みと情報発現
• 自然界における抗突然変異物質--生薬,茶,胎盤などにAntimutagen活性(今日の話題)

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