先天性胆道閉鎖症術後食道静脈瘤に対する内視鏡的硬化療法の合併症 : 門脈血栓形成を認めた1例

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We report a case of portal vein thrombosis(PVT) following endoscopic injection sclerotherapy(EIS) for esophageal varices in a 9-year-old male patient of postoperative congenital biliary atresia, together with a review of literatures. The patient complained of epigastralgia and vomiting on the 3 rd day after EIS. Laboratory studies showed marked increases of transaminase and WBC. A thrombus in the portal vein was detected by ultrasonography(US) as a high echoic mass and treated by administration of gabexate mesilate(FOY). We confirmed the disappearance of the thrombus by US on the 39th day after EIS. Twelve adult cases of PVT after EIS have been reported in Japanese literature. The case we report is the first case of PVT after EIS in childhood. We should take care of PVT as one of the severe complications of EIS. Routine US examination after EIS is preferable for early diagnosis and treatment of PVT.
1992-10-20